Recombinant human Cyclophilin-like 1/PPIL1 protein | NKMAX PPL0901 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Cyclophilin-like 1/PPIL1 protein

catalog :

PPL0901

quantity :

20 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Cyclophilin-like 1/PPIL1 protein

Domain :

1-166aa

Catalog number (SKU) :

PPL0901

NCBI :

NP_057143

Description :

Peptidylprolyl isomerase (cyclophilin) -like 1, also known as PPIL1, is a member of peptidyl-propyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. Human PPIL1 might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. So it is expected as a novel molecular target for colon-cancer therapy. Recombinant PPIL1, fused to His-tag at C-terminus, was expressed in E. coli and purified by conventional chromatography techniques.

Alternative Names :

Peptidyl-prolyl cis-trans isomerase-like 1, Peptidylprolyl isomerase like 1, Cyclophilin like 1, CYPL1, Rotamase PPIL1, PPIase

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Xu C., et al. (2006) J Biol Chem. 281(23):15900-8.;; Obama K., et al. (2006) Clin Cancer Res. 12(1):70-6.;;

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 700nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Human

Gene Category :

Heat Shock Proteins

Molecular Weight :

19.3 kDa (174aa) confirmed by MALDI-TOF

Bioactivity Comment and Pics :

Specific activity is > 700 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.

Amino Acid Sequence :

MAAIPPDSWQ PPNVYLETSM GIIVLELYWK HAPKTCKNFA ELARRGYYNG TKFHRIIKDF MIQGGDPTGT GRGGASIYGK QFEDELHPDL KFTGAGILAM ANAGPDTNGS QFFVTLAPTQ WLDGKHTIFG RVCQGIGMVN RVGMVETNSQ DRPVDDVKII KAYPSG

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9Y3C6

Internal Search Terms :

CGI-124, Cyclophilin related gene 1, Cyclophilin-like1, CYPL1, hCyPX, MGC678, Peptidylprolyl isomerase (cyclophilin) like 1, Peptidylprolyl isomerase (cyclophilin)-like 1, Peptidylprolyl isomerase (cyclophilin)-like 1 CGI124, peptidylprolyl isomerase like 1, PPIase, PPIL1, rotamase0, PPL0901-10ug, PPL0901-20ug, PPL0901-50ug, PPL0901-100ug, PPL0901-250ug, PPL0901-500ug, PPL0901-1mg, PPL0901-010, PPL0901-020, PPL0901-050, PPL0901-100, PPL0901-250, PPL0901-500, PPL0901-01M

more info or order :

NKMAX product webpage