Recombinant human PP2C gamma/PPM1G protein | NKMAX PPG0801 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PP2C gamma/PPM1G protein

catalog :

PPG0801

quantity :

20 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PP2C gamma/PPM1G protein

Domain :

317-546aa

Catalog number (SKU) :

PPG0801

NCBI :

NP_002698

Description :

PPM1G (Protein phosphatase 1G) is a member of the PP2C family of Serine/threonine protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The human Ser/Thr phosphatase PPM1G promotes spliceosome assembly. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Recombinant human PPM1G, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography techniques.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 25mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 1mM EDTA, 2mM beta-mercaptoethanol, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Marc Flajolet., et al. (2004). Proc. Natl. Acad. Sci. 100(26):16006-11.;; Suh EJ., et al. (2007). FEBS Lett. 580 (26):6100-4.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

27 kDa (250aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MEGKEEPGSD SGTTAVVALI RGKQLIVANA GDSRCVVSEA GKALDMSYDH KPEDEVELAR IKNAGGKVTM DGRVNGGLNL SRAIGDHFYK RNKNLPPEEQ MISALPDIKV LTLTDDHEFM VIACDGIWNV MSSQEVVDFI QSKISQRDEN GELRLLSSIV EELLDQCLAP DTSGDGTGCD NMTCIIICFK PRNTAELQPE SGKRKLEEVL STEGAEENGN SDKKKKAKRD

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O15355

Internal Search Terms :

Protein phosphatase, Mg2+/Mn2+ dependent 1G, Protein phosphatase Mg2+/Mn2+ dependent 1G, Protein phosphatase magnesium-dependent 1 gamma, Protein phosphatase magnesium dependent 1 gamma, Protein phosphatase 2C gamma isoform, Protein phosphatase 2 catalytic subunit gamma isoform, Protein phosphatase 1G, formerly 2C, magnesium-dependent, gamma isoform, Protein phosphatase 1G, Protein phosphatase 1C, PPP2CG, PPM1G, PPM1C, PP2Cgamma, PP2CG, PP2C gamma, PP2C g, PP2C, MGC2870, MGC1675, PPG0801-10ug, PPG0801-20ug, PPG0801-50ug, PPG0801-100ug, PPG0801-250ug, PPG0801-500ug, PPG0801-1mg, PPG0801-010, PPG0801-020, PPG0801-050, PPG0801-100, PPG0801-250, PPG0801-500, PPG0801-01M

more info or order :

NKMAX product webpage