protein

Recombinant human PDCD4 (S48Y) protein

PDC0801

20 ug

80 USD

Recombinant human PDCD4 (S48Y) protein

1-469aa

PDC0801

NP_055271

PDCD4 (Programmed cell death 4) encodes a tumor suppressor protein whose expression is lost in progressed carcinomas of lung, breast, colon, and prostate. The expression of PDCD4 gene is strongly induced during apoptosis in a number of cell types. It is modulated by cytokines in natural killer and T cells. Recombinant human PDCD4, was expressed in E. coli and purified by conventional chromatography techniques.

Programmed cell death 4 isoform 1, neoplastic transformation inhibitor, H731, MGC33046, MGC33047, Programmed cell death 4 isoform 1, PDPC4, Programmed cell death 4 isoform 1, PDCD4, programmed cell death 4 (neoplastic transformation inhibitor), nuclear antigen H731

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1M NaCl

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Yoshinaga H., et al. (1999) Pathol Int. 49(12):1067-77.;; Palamarchuk A., et al. (2006) Cancer Res. 65(24):11282-6.;;

> 90% by SDS-PAGE

SDS-PAGE

Human

Cancer

51 kDa (469aa) confirmed by MALDI-TOF

MDVENEQILN VNPADPDNLS DSLFSGDEEN AGTEEIKNEI NGNWISAYSI NEARINAKAK RRLRKNSSRD SGRGDSVSDS GSDALRSGLT VPTSPKGRLL DRRSRSGKGR GLPKKGGAGG KGVWGTPGQV YDVEEVDVKD PNYDDDQENC VYETVVLPLD ERAFEKTLTP IIQEYFEHGD TNEVAEMLRD LNLGEMKSGV PVLAVSLALE GKASHREMTS KLLSDLCGTV MSTTDVEKSF DKLLKDLPEL ALDTPRAPQL VGQFIARAVG DGILCNTYID SYKGTVDCVQ ARAALDKATV LLSMSKGGKR KDSVWGSGGG QQSVNHLVKE IDMLLKEYLL SGDISEAEHC LKELEVPHFH HELVYEAIIM VLESTGESTF KMILDLLKSL WKSSTITVDQ MKRGYERIYN EIPDINLDVP HSYSVLERFV EECFQAGIIS KQLRDLCPSR GRKRFVSEGD GGRLKPESY

Non-Tagged

E.coli

Recombinant Protein

Q53EL6

PDCD4 (S48Y), Programmed cell death 4 isoform 1, neoplastic transformation inhibitor, H731, MGC33046, MGC33047, Programmed cell death 4 isoform 1, PDPC4, Programmed cell death 4 isoform 1, PDCD4, programmed cell death 4 (neoplastic transformation inhibitor), nuclear antigen H731,PDC0801-10ug,PDC0801-20ug,PDC0801-50ug,PDC0801-100ug,PDC0801-250ug,PDC0801-500ug,PDC0801-1mg,PDC0801-10,PDC0801-20,PDC0801-50,PDC0801-100,PDC0801-250,PDC0801-500,PDC0801-1

Eto K, et al. Loss of programmed cell death 4 induces apoptosis by promoting the translation of procaspase-3 mRNA. (Cell Death Differ. 2012){https://pubmed.ncbi.nlm.nih.gov/21959934/}