product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Leptin/OB protein
catalog :
LEP0701
quantity :
20 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Leptin/OB protein
Domain :
22-167aa
Catalog number (SKU) :
LEP0701
NCBI :
NP_032519
Description :
Leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. Originally discovered in the mouse, the cDNA for leptin has been so far cloned from a variety of species including human, rat, cow, chicken, pig, sheep and dog. Recombinant mouse leptin was overexpressed as insoluble protein aggregate in E. coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer
Alternative Names :
LEP, OB, OBS, Leptin Mouse, Obesity factor, Obese protein, Leptin,
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Jeong KJ., et al. (1999) Appl Environ Microbiol. 65(7), 3027-32.;; Anini Y., et al. (2003) Diabetes. 52(2), 252-259.;; Hyogo H., et al. (2002) J. Biol. Chem. 277(37), 34117-34124.;;
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Hormones & Cytokines
Molecular Weight :
16 kDa (147aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC
Tag :
Non-Tagged
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P41160
Internal Search Terms :
Leptin, OB, LEP, OB, OBS, Leptin Mouse, Obesity factor, Obese protein, Leptin,LEP0701-10ug,LEP0701-20ug,LEP0701-50ug,LEP0701-100ug,LEP0701-250ug,LEP0701-500ug,LEP0701-1mg,LEP0701-10,LEP0701-20,LEP0701-50,LEP0701-100,LEP0701-250,LEP0701-500,LEP0701-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.