product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human CD158e/KIR3DL1 protein
catalog :
KIR3004
quantity :
20 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human CD158e/KIR3DL1 protein
Domain :
361-444aa
Catalog number (SKU) :
KIR3004
NCBI :
NP_037421
Description :
The three Ig-domain from of inhibitory killer cell Ig-like receptor 1 (KIR3DL1, NKB1, nkat3, p70KIR) is a NK cell receptor for polymorphic HLA-B determinant. KIR3DL1 recognizes the Bw4 determinant defined by sequence motifs at positins 77-83 of the HLA-B heavy chain. The cytoplasmic tail of KIR, which contains two immunoreceptor tyrosine-based inhibition motifs (ITIMs), mediates inhibitory signal transduction that prevents killer cell-mediated cytotoxicity. A His-tag fusion protein of KIR3DL1 cytoplasmic tail (361-444aa) was overexpressed as insoluble protein aggregates (inclusion bodies). This protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer
Alternative Names :
Killer cell immunoglobulin like receptor three Ig domains and long cytoplasmic tail 1, CD158 antigen-like family member E, HLA-BW4-specific inhibitory NK cell receptor, Natural killer-associated transcript 3, NKAT-3, p70 natural killer cell receptor clones CL-2/CL-11, p70 NK receptor CL-2/CL-11, cl-2, KIR, NKB1, cl-11, NKB1B, AMB11, CD158e1/2, CD158E1, CD158e2
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 25mM Tris-HCl buffer (pH 7.5) containing 100mM NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Chan HW., et al. (2003) J. Exp. Med. 197(2), 245-55.;; Gardiner CM., et al . (2001) J Immunol. 166(5):2992-3001.;;
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
15 kDa (132aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSTSGT IDKLDIEFHL WCSNKKNAAV MDQEPAGNRT ANSEDSDEQD PEEVTYAQLD HCVFTQRKIT RPSQRPKTPP TDTILYTELP NAKPRSKVVS CP
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P43629
Internal Search Terms :
KIR3DL1, Killer cell immunoglobulin-like receptor 3DL1, KIR3DL1, CD158E, NKAT3, NKB1, KIR3DL1 (Cytoplasmic tail, 361-444aa), MHC class I NK cell receptor, Natural killer-associated transcript 3, NKAT-3, p70 natural killer cell receptor clones CL-2/CL-11, HLA-BW4-specific inhibitory NK cell receptor, CD1, Killer cell immunoglobulin-like receptor 3DL1, Killer cell immunoglobulin-like receptor 3DL1 AMB11, CD158 antigen-like family member E, CD158e antigen, CD158E1, CD158E1/2, CD158E2, CL11, CL2, HLA-BW4-specific inhibitory NK cell receptor, killer cell immunoglobulin like receptor, Killer cell immunoglobulin like receptor three domains, short cytoplasmic tail, 1, Killer cell immunoglobulin like receptor three domains long cytoplasmic tail 1, KIR, KIR antigen 3DL1, KIR G1, KIR3DS1, Kirl1, Kirl2, Krl1, MGC119726, MGC119728, MGC126589, MGC126591, Natural killer associated transcript 3, Natural killer cell inhibitory receptor, NK receptor, NK-associated transcript 10, NK-associated transcript
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.