Recombinant human IPP-1/PPP1R1A protein | NKMAX IPP0801 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IPP-1/PPP1R1A protein

catalog :

IPP0801

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

citations: 1

Reference
Hashizume H, Fujiyama T, Kanebayashi J, Kito Y, Hata M, Yagi H. Skin recruitment of monomyeloid precursors involves human herpesvirus-6 reactivation in drug allergy. Allergy. 2013;68:681-9 pubmed publisher

product information

Product Type :

Proteins

Item Name :

Recombinant human IPP-1/PPP1R1A protein

Domain :

1-171aa

Catalog number (SKU) :

IPP0801

NCBI :

NP_006732

Description :

Protein phosphatase inhibitor-1 (IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase (PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B). Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Protein phosphatase inhibitor-1, Protein phosphatase inhibitor, Protein phosphatase inhibitor-1 Protein phosphatase inhibitor 1, I 1, I1, Inhibitor 1, IPP 1, IPP1, PPP1R1A, Protein phosphatase 1 regulatory (inhibitor) subunit 1A, Protein phosphatase 1 regulatory subunit 1A.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 50mM Tris-HCl buffer (pH 8.0) containing 0.1mM PMSF, 1mM EDTA, 1mM DTT, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Weiser DC., et al. (2004), J. Biol. Chem. 279(47):48904-14;; Rodriguez P., et al. (2006), J. Biol. Chem. 281(50):38599-608;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

20kDa (179aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE PEGAAESTGT QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE PSTKEPSTHI PPLDSKGANS VLEHHHHHH

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q13522

Internal Search Terms :

IPP1, Protein phosphatase inhibitor-1, Protein phosphatase inhibitor, Protein phosphatase inhibitor-1 Protein phosphatase inhibitor 1, I 1, I1, Inhibitor 1, IPP 1, IPP1, PPP1R1A, Protein phosphatase 1 regulatory (inhibitor) subunit 1A, Protein phosphatase 1 regulatory subunit 1A.,IPP0801-10ug,IPP0801-20ug,IPP0801-50ug,IPP0801-100ug,IPP0801-250ug,IPP0801-500ug,IPP0801-1mg,IPP0801-10,IPP0801-20,IPP0801-50,IPP0801-100,IPP0801-250,IPP0801-500,IPP0801-1

more info or order :

NKMAX product webpage