protein

Recombinant human IL-8/CXCL8 protein

ILH0501

20 ug

55 USD

Recombinant human IL-8/CXCL8 protein

23-99aa

ILH0501

NP_000575.1

Interleukin-8 (IL-8) is a chemokine, a member of the cytokine family that displays chemotactic activity for specific types of leukocytes. It is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes, and various tumor cell lines, can produce CXCL8/IL-8 in response to a wide variety of pro-inflammatory stimuli such as exposure to IL-1, TNF, LPS, and viruses. Recombinant human IL-8 was expressed in E. coli and purified by using conventional chromatography techniques.

C-X-C motif chemokine ligand 8, Interleukin-8, IL-8, C-X-C motif chemokine 8, Emoctakin, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil chemotactic factor, MDNCF, Monocyte-derived neutrophil-activating peptide, MONAP, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, T-cell chemotactic factor, Lung giant cell carcinoma-derived chemotactic protein, Tumor necrosis factor-induced gene 1, Lymphocyte derived neutrophil activating peptide, Beta endothelial cell-derived neutrophil activating peptide, Alveolar macrophage chemotactic factor I, SCYB8, LUCT, LECT, TSG-1, AMCF-I, LYNAP, NAF, b-ENA

1mg/ml (determined by BCA assay)

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Mukaida, N., et al.(1992)Microbiol. Immunol. 36, 773-789 ;; Larsen, C.G., et al. (1989). Science, 243, 1464-1466;; Baldwin ET., et al. (1990). J Biol Chem. 265(12):6851-6853 ;;

> 95% by SDS-PAGE

SDS-PAGE

Human

Hormones & Cytokines

9 kDa (78aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

MAVLPRSAKE LRCQCIKTYS KPFHPKFIKE LRVIESGPHC ANTEIIVKLS DGRELCLDPK ENWVQRVVEK FLKRAENS

Non-Tagged

E.coli

Recombinant Protein

P10145

IL8, CXCL8, CXCL8, Neurophil chemotactic factor, NCF, Neutrophil activating protein, NAP, Monocyte derived neutrophil chemotactic factor, MDNCF, T-lymphocyte chemotactic factor, TCF, Granulocyte chemotactic protein, GCP, and Leukocyte adhension inhibitor, LAI, NAP 1, 3 10C, 310C, AMCF 1, AMCF1, b ENAP, Beta thromboglobulin like protein, CXC chemokine ligand 8, CXCL 8, Emoctakin, GCP 1, GCP1, Granulocyte chemotactic protein 1, IL 8, Inteleukin 8, Interleukin8, K 60, LECT, LuCT, Lymphocyte derived neutrophil activating factor, LYNAP, MDNCF, MDNCF a, MDNCF alpha, MONAP, Monocyte derived neutrophil activating protein, Monocyte derived neutrophil chemotactic factor, NAF, NAP1, Neutrophil activating factor, Neutrophil activating protein 1, Protein 3 10C, SCYB 8, SCYB8, T cell chemotactic factor, TSG 1, TSG1, il8,ILH0501-10ug,ILH0501-20ug,ILH0501-50ug,ILH0501-100ug,ILH0501-250ug,ILH0501-500ug,ILH0501-1mg,ILH0501-10,ILH0501-20,ILH0501-50,ILH0501-100,ILH0501-250,ILH0501-500,ILH0501-1

Kim HR, et al. Anti-cancer activity and mechanistic features of a NK cell activating molecule. (Cancer Immunol Immunother. 2009){https://pubmed.ncbi.nlm.nih.gov/19259669/}