Recombinant human IL-1Ra/IL1RN protein | NKMAX ILA0501 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-1Ra/IL1RN protein

catalog :

ILA0501

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-1Ra/IL1RN protein

Domain :

26-177aa

Catalog number (SKU) :

ILA0501

NCBI :

NP_776214

Description :

One of the most potent pro-inflammatory mediators is the early-acting cytokine interleukin-1 (IL-1), whose actions are regulated by the structurally related IL-1 receptor antagonist (IL-1 RA). IL-1 RA is a competitive IL-1 inhibitor and a powerful anti-inflammatory agent. Also, Several autoimmune and inflammatory diseases have been associated with an allelic polymorphism of the IL-1 RA gene. Recombinant human IL-1 RA was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, IL1F3, IL1RA

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Capper., et al. (2004) Clin. Exp. Immunol. 138:348 ;; Roberge CJ., et al. (1994) Journal of Immunology. 152: 5485-94 ;; Carter DB., et al. (1990) Nature. 344: 633-7 ;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

17.2 kDa (153aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P18510

Internal Search Terms :

IL1ra, IL1F3, IL1RN, IL1F3, IL1RA, Interleukin-1 receptor antagonist, IL-1ra, IL-1RN, IRAP, IL1 inhibitor, ICIL-1RA, Anakinra, Interleukin-1 receptor antagonist protein, ICIL 1RA, IL1 inhibitor, ICIL1RA,ILA0501-10ug,ILA0501-20ug,ILA0501-50ug,ILA0501-100ug,ILA0501-250ug,ILA0501-500ug,ILA0501-1mg,ILA0501-10,ILA0501-20,ILA0501-50,ILA0501-100,ILA0501-250,ILA0501-500,ILA0501-1

more info or order :

NKMAX product webpage