Recombinant human IFN-alpha 2/IFNA2 protein | NKMAX IFN0502 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IFN-alpha 2/IFNA2 protein

catalog :

IFN0502

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IFN-alpha 2/IFNA2 protein

Domain :

24-188aa

Catalog number (SKU) :

IFN0502

NCBI :

NP_000596.2

Description :

Interferon induces a variety of effects on target cells including antiviral, antiproliferative, and immunomodulatory activities. Interferon alpha-2b can either inhibit or enhance immune cell activity within the tightly regulated microenvironment of inflammation, depending upon the concentration of the cytokine and the activation stage of the cell. Interferon alpha-2b was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Alternative Names :

Interferon alpha 2, IFN-alpha-2, Interferon alpha-A, IFNA, IFN-alphaA, LeIF A, IFNA2A, IFNA2B, IFNA2C, alpha-2a interferon, Interferon alpha 2b

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4), 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Mire-Sluis AR., et al, (1996) J. Immunol. Methods.195, 55-61.;; Rubinstein S., et al. (1981) J. Virol. 37, 755-758.;;

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human IFN-alpha/beta R2 (CAT# ATGP3952) in the presence of Human IFN-alpha/beta R1 (CAT# ATGP3894).

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

19.4 kDa (166aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human IFN-alpha 2 is coated at 10 ug/ml (100 ul/well) can bind Human IFN-alpha/beta R2 (CAT# ATGP3952) in the presence of Human IFN-alpha/beta R1 (CAT# ATGP3894).

Amino Acid Sequence :

MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P01563

Internal Search Terms :

IFN-a2, Interferon a-2b, IRF-2-binding protein 1, Interferon regulatory factor 2-binding protein 1, interferon regulatory factor 2 binding protein 1, DKFZP434M154,IFN0502-10ug,IFN0502-20ug,IFN0502-50ug,IFN0502-100ug,IFN0502-250ug,IFN0502-500ug,IFN0502-1mg,IFN0502-10,IFN0502-20,IFN0502-50,IFN0502-100,IFN0502-250,IFN0502-500,IFN0502-1

References with this Product :

Kim HR, et al. Anti-cancer activity and mechanistic features of a NK cell activating molecule. (Cancer Immunol Immunother. 2009){https://pubmed.ncbi.nlm.nih.gov/19259669/} {}

more info or order :

NKMAX product webpage