product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human FIH-1/HIF-1AN protein
catalog :
HIF0904
quantity :
20 ug
price :
55 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human FIH-1/HIF-1AN protein
Domain :
1-349aa
Catalog number (SKU) :
HIF0904
NCBI :
NP_060372
Description :
Hypoxia-inducible factor 1, alpha subunit inhibitor (HIF1AN), a member of the Fe2+ and 2-oxoglutarate-dependent dioxygenase superfamily, is protein that hydoxylates a specific asparagine residue (Asn-803) within the HIF1alpha C-terminal transactivation domain. In normoxia, the HIF1AN-mediated hydroxylation of the HIF1alpha transactivation domain results in blockage of the HIF1alpha-p300/CBP interaction and represses transcriptional activity of HIF1alpha-targeted genes. Recombinant human HIF1AN protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Hypoxia-inducible factor 1 alpha subunit inhibitor, Hypoxia-inducible factor asparagine hydroxylase, Factor inhibiting HIF-1, FIH1, Hypoxia-inducible factor 1, alpha subunit inhibitor Hypoxia inducible factor asparagine hydroxylase, Factor inhibiting HIF1, FIH 1, FLJ20615, FLJ22027, Hypoxia inducible factor 1 alpha inhibitor, Hypoxia inducible factor 1 alpha subunit inhibitor, Peptide aspartate beta dioxygenase, DKFZp762F1811, Hypoxia-Inducible Factor-1 Alpha Inhibitor
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0)
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Fukuba H., et al. (2008) Neurosci Lett. 433(3):209-14.;; Li J., et al. (2007) Mol Cell Biol. 27(20):7345-53.;;
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cell Cycle
Molecular Weight :
40.2 kDa (349aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MAATAAEAVA SGSGEPREEA GALGPAWDES QLRSYSFPTR PIPRLSQSDP RAEELIENEE PVVLTDTNLV YPALKWDLEY LQENIGNGDF SVYSASTHKF LYYDEKKMAN FQNFKPRSNR EEMKFHEFVE KLQDIQQRGG EERLYLQQTL NDTVGRKIVM DFLGFNWNWI NKQQGKRGWG QLTSNLLLIG MEGNVTPAHY DEQQNFFAQI KGYKRCILFP PDQFECLYPY PVHHPCDRQS QVDFDNPDYE RFPNFQNVVG YETVVGPGDV LYIPMYWWHH IESLLNGGIT ITVNFWYKGA PTPKRIEYPL KAHQKVAIMR NIEKMLGEAL GNPQEVGPLL NTMIKGRYN
Tag :
Non-Tagged
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9NWT6
Internal Search Terms :
FIH1, HIF1AN,HIF0904-10ug,HIF0904-20ug,HIF0904-50ug,HIF0904-100ug,HIF0904-250ug,HIF0904-500ug,HIF0904-1mg,HIF0904-10,HIF0904-20,HIF0904-50,HIF0904-100,HIF0904-250,HIF0904-500,HIF0904-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.