Recombinant human Growth Hormone 1/GH1 protein | NKMAX GRH3001 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Growth Hormone 1/GH1 protein

catalog :

GRH3001

quantity :

20 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Growth Hormone 1/GH1 protein

Domain :

27-217aa

Catalog number (SKU) :

GRH3001

NCBI :

NP_000506

Description :

Human growth hormone (hGH, somatotropin), a protein hormone from the anterior lobe of the pituitary gland, comprises a single polypeptide chain of 191 amino acid residues. The growth hormone amino acid sequence varies considerably between species, and non-primate growth hormones have little activity in man. Its main function is the stimulation of somatic and bone growth, as well as an increase in the size and mass of organs and tissues. Recombinant human growth hormone (rhGH ) was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Alternative Names :

GH, GH1, GHN, GH-N, Growth hormone, Growth hormone 1, hGH-N, Pituitary growth hormone, Somatotropin

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) 88mM mannitol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wickens., et al.(1978) J. Biol Chem. 253(7):2483-2495;; Goeddel. et al.(1979) Proc. Natl. Acad. Sci. 76:106-110;; Chang, et al. (1978) Nature 275:617-624 ;; ullrich. et al. (1977) Science 196:1313-1319.;;

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range ≤ 0.2ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

22.2 kDa (192aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human Growth Hormon Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range ≤ 0.2ng/ml.

Amino Acid Sequence :

MFPTIPLSRL FDNAMLRAHR LHQLAFDTYQ EFEEAYIPKE QKYSFLQNPQ TSLCFSESIP TPSNREETQQ KSNLELLRIS LLLIQSWLEP VQFLRSVFAN SLVYGASDSN VYDLLKDLEE GIQTLMGRLE DGSPRTGQIF KQTYSKFDTN SHNDDALLKN YGLLYCFRKD MDKVETFLRI VQCRSVEGSC GF

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P01241

Internal Search Terms :

GH, GH 1, GH1, GHN, GH-N, Growth Hormone, Growth hormone 1, hGH-N, Pituitary growth hormone, Somatotropin, GRH3001-10ug, GRH3001-20ug, GRH3001-50ug, GRH3001-100ug, GRH3001-250ug, GRH3001-500ug, GRH3001-1mg, GRH3001-010, GRH3001-020, GRH3001-050, GRH3001-100, GRH3001-250, GRH3001-500, GRH3001-01M

References with this Product :

Lee EN, et al. Stabilizing peptide fusion for solving the stability and solubility problems of therapeutic proteins. Pharm Res. 2005 Oct;22(10):1735-46. {https://pubmed.ncbi.nlm.nih.gov/16180132/}

more info or order :

NKMAX product webpage