Recombinant human Geminin protein | NKMAX GMN0601 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Geminin protein

catalog :

GMN0601

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Geminin protein

Domain :

1-209aa

Catalog number (SKU) :

GMN0601

NCBI :

NP_056979.1

Description :

Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.

Alternative Names :

GMNN, Geminin, Geminin, DNA replication inhibitor, Gem, Geminin DNA replication inhibitor, OTTHuMP00000039393, RP3 369A17.3.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

McGarry TJ. et al (1998) Cell. 93(6):1043-53.;; Pitulescu M. et al (2005) Cell Mol Life Sci. 62(13):1425-33.;; Luo L. et al (2004) Nature. 427(6976):749-53;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

27.6 kDa (245aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MNPS MKQKQEEIKE NIKNSSVPRR TLKMIQPSAS GSLVGRENEL SAGLSKRKHR NDHLTSTTSS PGVIVPESSE NKNLGGVTQE SFDLMIKENP SSQYWKEVAE KRRKALYEAL KENEKLHKEI EQKDNEIARL KKENKELAEV AEHVQYMAEL IERLNGEPLD NFESLDNQEF DSEEETVEDS LVEDSEIGTC AEGTVSSSTD AKPCI

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O75496

Internal Search Terms :

Geminin, GMNN, Geminin, Geminin, DNA replication inhibitor, Gem, Geminin DNA replication inhibitor, OTTHuMP00000039393, RP3 369A17.3.,GMN0601-10ug,GMN0601-20ug,GMN0601-50ug,GMN0601-100ug,GMN0601-250ug,GMN0601-500ug,GMN0601-1mg,GMN0601-10,GMN0601-20,GMN0601-50,GMN0601-100,GMN0601-250,GMN0601-500,GMN0601-1

more info or order :

NKMAX product webpage