Recombinant human Gankyrin/PSMD10 protein | NKMAX GAN0901 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Gankyrin/PSMD10 protein

catalog :

GAN0901

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Gankyrin/PSMD10 protein

Domain :

1-226aa

Catalog number (SKU) :

GAN0901

NCBI :

NP_002805

Description :

Gankyrin is an oncoprotein commonly overexpressed in most hepatocellular carcinomas. Gankyrin interacts with S6 ATPase of the 19S regulatory particle of the 26S proteasome. It is known to play a role in the regulation of the phosphorylation of the retinoblastoma protein by CDK4, and to enhance the ubiquitinylation of p53 by MDM2. Gankyrin consists of 7 ankyrin repeats and is structurally similar to I kappa Bs. Recombinant human Gankyrin was expressed in E. coli and purified by conventional chromatography techniques.

Alternative Names :

proteasome 26S subunit non ATPase 10 (PSMD10) isoform 1, ankyrin repeat protein p28, Gankyrin, 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit p28, PSMD10.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

umemura A., et al. (2008) Hepatology. 47(2):493-502.;; Chen Y., et al. (2007) Cell Res. 17(12): 1020-9;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

24.4 kDa (226aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA GHTEIVEFLL QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN AVNQNGCTPL HYAASKNRHE IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG NLKMIHILLY YKASTNIQDT EGNTPLHLAC DEERVEEAKL LVSQGASIYI ENKEEKTPLQ VAKGGLGLIL KRMVEG

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O75832

Internal Search Terms :

Gankyrin,GAN0901-10ug,GAN0901-20ug,GAN0901-50ug,GAN0901-100ug,GAN0901-250ug,GAN0901-500ug,GAN0901-1mg,GAN0901-10,GAN0901-20,GAN0901-50,GAN0901-100,GAN0901-250,GAN0901-500,GAN0901-1

more info or order :

NKMAX product webpage