protein

Recombinant human FABP4/A-FABP protein

FAB0802

20 ug

105 USD

Recombinant human FABP4/A-FABP protein

1-132aa

FAB0802

NP_001433.1

Fatty acid-binding protein 4 (FABP4), known as adipocyte FABP (A-FABP) or aP2, is a carrier protein for fatty acids that is primarily expressed in adipocyte and macrophages. FABP4 is secreted from adipocytes in a non-classical pathway associated with lipolysis and acts as an adipokine for the development of insulin resistance and atherosclerosis. Circulating FABP4 levels are associated with several aspects of metabolic syndrome and cardiovascular disease. Blocking this protein either through genetic engineering or drugs has the possibility of treating heart disease and the metabolic syndrome. Recombinant human FABP4 protein, was expressed in E. coli and purified by using conventional chromatography techniques.

Fatty acid binding protein 4, IL-1 alpha, Hematopoietin-1, A-FABP, ALBP, FABP4, Fatty acid binding protein 4 adipocyte, AP2

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 2mM EDTA, 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Furuhashi M., et al. (2007).Nature. 447(7147):959-65;; Shum BO., et al. (2006).J Clin Invest. 116(8):2183-2192;;

> 95% by SDS-PAGE

SDS-PAGE

Human

Hormones & Cytokines

14.7 kDa (132aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

MCDAFVGTWK LVSSENFDDY MKEVGVGFAT RKVAGMAKPN MIISVNGDVI TIKSESTFKN TEISFILGQE FDEVTADDRK VKSTITLDGG VLVHVQKWDG KSTTIKRKRE DDKLVVECVM KGVTSTRVYE RA

Non-Tagged

E.coli

Recombinant Protein

P15090

IL-1A, IL1A, IL-1 alpha, IL1 alpha, IL 1A, IL 1 alpha, IL 1 A, Hematopoietin-1, Hematopoietin1, Hematopoietin 1, Fatty acid binding protein 4 adipocyte, Fatty acid binding protein 4, FABP4, AP2, ALBP, A-FABP, AFABP, A FABP, FAB0802-10ug, FAB0802-20ug, FAB0802-50ug, FAB0802-100ug, FAB0802-250ug, FAB0802-500ug, FAB0802-1mg, FAB0802-010, FAB0802-020, FAB0802-050, FAB0802-100, FAB0802-250, FAB0802-500, FAB0802-01M