Recombinant human Calcipressin-1/DSCR1 protein | NKMAX DSR0701 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Calcipressin-1/DSCR1 protein

catalog :

DSR0701

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Calcipressin-1/DSCR1 protein

Domain :

1-117aa

Catalog number (SKU) :

DSR0701

NCBI :

NP_981962.1

Description :

The Down's syndrome candidate region 1 (DSCR1) protein, encoded by a gene located in the human chromosome 21, interacts with calcineurin and is overexpressed in Down's syndrome patients. DSCR1 Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A, possibly affecting central nervous system development. DSCR isoform b is shorter at the N-terminus compared to isoform a. Recombinant human DSCR1 was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Calcipressin 1 isoform b, Regulator of calcineurin 1, RCAN1, Down syndrome critical region gene 1, DSCR1, Adapt78, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, CSP1, DSC1

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl, 1mM DTT, 10% Glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Hesser BA., et al. (2004) Blood. 104(1):149-58;; Harris CD., et al. (2007) FEBS J. 274(7):1715-24.;;

Purity :

> 90% by SDS-PAGE

Additional Info Comment and Pic :

Additional Info Comment and Pic

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

13.2 kDa (117aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGP GEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P53805

Internal Search Terms :

DSCR1 isoform b, Down syndrome candidate region 1, Down syndrome candidate region 1, Down syndrome critical region protein 1, adapt78 protein, calcipressin 1, Calcipressin 1 isoform b, Down syndrome candidate region 1,DSR0701-10ug,DSR0701-20ug,DSR0701-50ug,DSR0701-100ug,DSR0701-250ug,DSR0701-500ug,DSR0701-1mg,DSR0701-10,DSR0701-20,DSR0701-50,DSR0701-100,DSR0701-250,DSR0701-500,DSR0701-1

more info or order :

NKMAX product webpage