Recombinant human Desert Hedgehog/Dhh N-terminus protein

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Desert Hedgehog/Dhh N-terminus protein

catalog :

DHH0901

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Desert Hedgehog/Dhh N-terminus protein

Domain :

23-198aa

Catalog number (SKU) :

DHH0901

NCBI :

NP_066382

Description :

DHH belongs to the hedgehog family. The C-terminal domain displays an autoproteolysis activity and a cholesterol transferase activity. The N- terminal domain is the active species in both local and long-range signaling, whereas the C-terminal domain has no signaling activity. This protein is produced by Sertoli cells and may be involved in both male gonadal differentiation and perineurial development. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. Recombinant DHH protein was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

desert hedgehog preproprotein, Drosophila, HHG-3, MGC35145, Desert hedgehog protein N-product, DHH, desert hedgehog preproprotein Desert hedgehog, Desert hedgehog (Drosophila) homolog, Desert hedgehog homolog (Drosophila), Desert hedgehog protein precursor.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM MES buffer (pH 5.5) containing 0.5mM DTT, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Chen YJ, et al. (2007). Cell Cycle. 6(15):1826-30;; Van den Brink GR., et al. (2007). Physiol Rev. 87(4):1343-75;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

22 kDa (197aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MCGPGRGPVG RRRYARKQLV PLLYKQFVPG VPERTLGASG PAEGRVARGS ERFRDLVPNY NPDIIFKDEE NSGADRLMTE RCKERVNALA IAVMNMWPGV RLRVTEGWDE DGHHAQDSLH YEGRALDITT SDRDRNKYGL LARLAVEAGF DWVYYESRNH VHVSVKADNS LAVRAGG

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O43323

Internal Search Terms :

Desert Hedgehog, Dhh N-terminus, desert hedgehog preproprotein, Drosophila, HHG-3, MGC35145, Desert hedgehog protein N-product, DHH, desert hedgehog preproprotein Desert hedgehog, Desert hedgehog (Drosophila) homolog, Desert hedgehog homolog (Drosophila), Desert hedgehog protein precursor.,DHH0901-10ug,DHH0901-20ug,DHH0901-50ug,DHH0901-100ug,DHH0901-250ug,DHH0901-500ug,DHH0901-1mg,DHH0901-10,DHH0901-20,DHH0901-50,DHH0901-100,DHH0901-250,DHH0901-500,DHH0901-1

more info or order :

NKMAX product webpage