Recombinant human Cyclophilin 40/PPID protein | NKMAX CYP0801 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Cyclophilin 40/PPID protein

catalog :

CYP0801

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Cyclophilin 40/PPID protein

Domain :

1-370aa

Catalog number (SKU) :

CYP0801

NCBI :

NP_005029

Description :

Cyclophilin D (also known as peptidylpropyl isomerase D, PPID) is a member of peptidyl-propyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. This protein can bind to the immunosuppressant cyclosporine A and was known that its overexpression suppresses the apoptosis in cancer cells. Recombinant human cyclophilin D was expressed in E. coli and purified by conventional chromatography techniques.

Alternative Names :

Peptidyl-prolyl cis-trans isomerase D, Peptidylprolyl isomerase D, 40 kDa peptidyl-prolyl cis-trans isomerase, PPIase D, Cyclophilin-related protein, Rotamase D, CYP-40, CypD, Cyclophilin D

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Machida K., et al.(2006) J. Biol. Chem. 281(20):14314-20. ;; Yokoi H., et al.(1996) Genomics 35(3):448-55. ;;

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 700nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

42.9 kDa (390aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Specific activity is > 700 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.

Amino Acid Sequence :

MSHPSPQAKP SNPSNPRVFF DVDIGGERVG RIVLELFADI VPKTAENFRA LCTGEKGIGH TTGKPLHFKG CPFHRIIKKF MIQGGDFSNQ NGTGGESIYG EKFEDENFHY KHDREGLLSM ANAGRNTNGS QFFITTVPTP HLDGKHVVFG QVIKGIGVAR ILENVEVKGE KPAKLCVIAE CGELKEGDDG GIFPKDGSGD SHPDFPEDAD IDLKDVDKIL LITEDLKNIG NTFFKSQNWE MAIKKYAEVL RYVDSSKAVI ETADRAKLQP IALSCVLNIG ACKLKMSNWQ GAIDSCLEAL ELDPSNTKAL YRRAQGWQGL KEYDQALADL KKAQGIAPED KAIQAELLKV KQKIKAQKDK EKAVYAKMFA

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q08752

Internal Search Terms :

Cyclophilin40, PPID, Peptidylprolyl isomerase D, PPID, CYPD, CYP-40, Cyclophilin D, 40 kDa peptidyl prolyl cis trans isomerase, 40 kDa peptidyl prolyl cis trans isomerase D, Cyclophilin related protein, Cyclophilin40, CyclophilinD, CYP 40, CYP40, MGC33096.Peptidylprolyl isomerase D, PPIase, PPID, Rotamase.,CYP0801-10ug,CYP0801-20ug,CYP0801-50ug,CYP0801-100ug,CYP0801-250ug,CYP0801-500ug,CYP0801-1mg,CYP0801-10,CYP0801-20,CYP0801-50,CYP0801-100,CYP0801-250,CYP0801-500,CYP0801-1

more info or order :

NKMAX product webpage