Recombinant human Complexin-1 protein | NKMAX CPX0901 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Complexin-1 protein

catalog :

CPX0901

quantity :

20 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Complexin-1 protein

Domain :

1-134aa

Catalog number (SKU) :

CPX0901

NCBI :

NP_006642

Description :

Complexin1 belongs to a family of SNARE complex binding proteins that were suggested to be either facilitators or inhibitors of vesicle exocytosis. Complexin 1 exhibits reduced Ca2+-triggered fast neurotransmitter release at hippocampal glutamatergic synapses, indicating that this protein is a positive regulator of transmitter release. In contrast, it inhibits SNARE-mediated liposome and cell fusions in vitro, which lead to the hypothesis that it acts as fusion clamps of synaptic exocytosis. Recombinant Complexin 1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

CPXL1, CPX1, Synaphin-2, Complexin 1, Complexin I, CPX1, Synaphin 2,

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Salimi K, et al. (2008) Synapse, 273-82;; Giraudo CG, et al. (2006) Science, 676-80;; Tang J, et al. (2006) Cell, 1175-87;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

17.1 kDa (154aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MEFVMKQALG GATKDMGKML GGDEEKDPDA AKKEEERQEA LRQAEEERKA KYAKMEAERE AVRQGIRDKY GIKKKEEREA EAQAAMEANS EGSLTRPKKA IPPGCGDEVE EEDESILDTV IKYLPGPLQD MLKK

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O14810

Internal Search Terms :

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more info or order :

NKMAX product webpage