Recombinant human CCL2/MCP-1 protein | NKMAX CCL0905 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CCL2/MCP-1 protein

catalog :

CCL0905

quantity :

20 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CCL2/MCP-1 protein

Domain :

24-99aa

Catalog number (SKU) :

CCL0905

NCBI :

NP_002973

Description :

Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Recombinant human CCL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

C-C motif chemokine ligand 2, Small inducible cytokine A2, SCYA2, Monocyte chemotactic protein 1 homologous to mouse Sig-je, Monocyte chemotactic and activating factor, Monocyte secretory protein JE, Small inducible cytokine subfamily A member 2, MCP1, MCP-1, MCAF, SMC-CF, GDCF-2, HC11, MGC9434

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Serbina NV., et al. (2008) Annu Rev Immunol. 26:421-52;; Rafei M., et al. (2009) J Immunol. 182(10):5994-6002;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

10.9 kDa (97aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MQPDAINAPV TCCYNFTNRK ISVQRLASYR RITSSKCPKE AVIFKTIVAK EICADPKQKW VQDSMDHLDK QTQTPKT

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P13500

Internal Search Terms :

CCL2, MCP1, Chemokine (C-C motif) ligand 2, MCAF, GDCF-2, HC11, SCYA2, Chemokine (C-C motif) ligand 2, CCL2, small inducible cytokine A2 (monocyte chemotactic protein 1 homologous to mouse Sig-je), MCP1, MCP-1, SMC-CF, MGC9434,CCL0905-10ug,CCL0905-20ug,CCL0905-50ug,CCL0905-100ug,CCL0905-250ug,CCL0905-500ug,CCL0905-1mg,CCL0905-10,CCL0905-20,CCL0905-50,CCL0905-100,CCL0905-250,CCL0905-500,CCL0905-1

more info or order :

NKMAX product webpage