Recombinant human CEBP alpha/CEBPA protein | NKMAX CBP3001 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CEBP alpha/CEBPA protein

catalog :

CBP3001

quantity :

20 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CEBP alpha/CEBPA protein

Domain :

270-358aa

Catalog number (SKU) :

CBP3001

NCBI :

NP_004355

Description :

CCAAT/enhancer binding protein (C/EBP) alpha is a family of transcription factors that all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP alpha, beta, gamma, delta, that form homodimers and that form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein; a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBPs differ significantly in their physiological functions and in their downstream target genes. For example, mice lacking C/EBP alpha die shortly after birth due to severe hypoglycemia and the absence of glycogen storage in liver, whereas knockout of C/EBPbeta causes defects in female reproduction The bZip region of CEBP-alpha (residues 270-358) was produced in E. coli and purified by ion-exchange chromatography and FPLC gel-filtration chromatography.

Alternative Names :

CCAAT/enhancer-binding protein alpha, C/EBP alpha, CEBP

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl, 5mM beta-Mercaptoethanol.

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Subramanian,L., et.al.(2003) J.Biol.Chem. 278(11) 9134 - 9141;; Gombart,A.F., et al (2002) Blood 99(4) 1332-1340;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

14.5 kDa (126aa) confirmed by MALDI-TOF

Amino Acid Sequence :

GAG KAKKSVDKNS NEYRVRRERN NIAVRKSRDK AKQRNVETQQ KVLELTSDND RLRKRVEQLS RELDTLRGIF RQLPESSLVK AMGNCA

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P49715

Internal Search Terms :

CEBP a, CCAAT/enhancer binding protein a, CEBPA, CEBP-alpha bZIPregion residues 270-358, C/EBP alpha, CCAAT/enhancer-binding protein alpha, CAAT/enhancer binding protein a, Apoptotic cysteine protease, Apoptotic protease Mch 5, CAP4, Caspase 8 precursor, CCAAT Enhancer Binding Protein alpha, CEBP, CEBP A, CEBP alpha, FADD homologous ICE/CED 3 like protease, FADD like ICE, FLICE, ICE8, MACH, MCH5, MORT1 associated CED 3 homolog,CBP3001-10ug,CBP3001-20ug,CBP3001-50ug,CBP3001-100ug,CBP3001-250ug,CBP3001-500ug,CBP3001-1mg,CBP3001-10,CBP3001-20,CBP3001-50,CBP3001-100,CBP3001-250,CBP3001-500,CBP3001-1

more info or order :

NKMAX product webpage