protein

Recombinant human BMP-2 (monomer) protein

BMP0905

20 ug

80 USD

Recombinant human BMP-2 (monomer) protein

283-396aa

BMP0905

NP_001191.1

BMP-2 (Bone morphogenetic protein 2) is multi-functional growth factors that belong to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility. Recombinant human BMP-2 protein was expressed in E. coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer.

Bone morphogenetic protein 2, BMP-2A

0.5mg/ml (determined by Bradford assay)

Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Chen D., et al. (2004). Growth factors. 22(4):233-41;; Schliephake H., et al. (2005). Clin Oral Implants Res. 17(6):666-72;;

> 90% by SDS-PAGE

SDS-PAGE

Human

Hormones & Cytokines

13 kDa (115aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR

Non-Tagged

E.coli

Recombinant Protein

P12643

CD159 antigen-like family member A, Bone Morphogenetic protein-2, Bone morphogenetic Protein 2, BMP-2A, BMP2A, BMP2 (monomer), BMP2, BMP0905-10ug, BMP0905-20ug, BMP0905-50ug, BMP0905-100ug, BMP0905-250ug, BMP0905-500ug, BMP0905-1mg, BMP0905-010, BMP0905-020, BMP0905-050, BMP0905-100, BMP0905-250, BMP0905-500, BMP0905-01M

Tanaka M, et al. Physico-Chemical, In Vitro, and In Vivo Evaluation of a 3D Unidirectional Porous Hydroxyapatite Scaffold for Bone Regeneration. (Materials (Basel). 2017){https://pubmed.ncbi.nlm.nih.gov/28772390/};;Tanaka M, et al. In Vitro and In Vivo Evaluation of a Three-Dimensional Porous Multi-Walled Carbon Nanotube Scaffold for Bone Regeneration. (Nanomaterials (Basel). 2017){https://pubmed.ncbi.nlm.nih.gov/28336879/};;Qi S, et al. Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells. (Small. 2019){https://pubmed.ncbi.nlm.nih.gov/30488562/}