Recombinant human BMP-4 (monomer) protein | NKMAX BMP0904 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human BMP-4 (monomer) protein

catalog :

BMP0904

quantity :

20 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human BMP-4 (monomer) protein

Domain :

293-408aa

Catalog number (SKU) :

BMP0904

NCBI :

NP_001193.2

Description :

Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic protein family which belongs to the TGF-beta superfamily. This protein is a vital regulatory molecule that functions throughout bone and cartilage development, specifically tooth development, limb formation, bone induction, and fracture repair. In human embryonic development, BMP- 4 is required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. And it is overexpressed in patients with fibrodysplasia ossificans progressiva. Recombinant BMP-4 was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Alternative Names :

ZYME, DVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP4, BMP2B1, BMP2B

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Moon BS., et al. (2009) Exp Mol Med. 41(2):116-25.;; Li BC., et al. (2009) J Trauma. 66(2):450-6;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

13.2 kDa (117aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MSPKHHSQRA RKKNKNCRRH SLYVDFSDVG WNDWIVAPPG YQAFYCHGDC PFPLADHLNS TNHAIVQTLV NSVNSSIPKA CCVPTELSAI SMLYLDEYDK VVLKNYQEMV VEGCGCR

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P12644

Internal Search Terms :

ZYME, DVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP4 (monomer), BMP4, BMP2B1, BMP-2B, BMP2B, BMP 4, BMP0904-10ug, BMP0904-20ug, BMP0904-50ug, BMP0904-100ug, BMP0904-250ug, BMP0904-500ug, BMP0904-1mg, BMP0904-010, BMP0904-020, BMP0904-050, BMP0904-100, BMP0904-250, BMP0904-500, BMP0904-01M

more info or order :

NKMAX product webpage