Human LYVE-1 antibody | NKMAX AXL0610 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human LYVE-1 antibody

catalog :

AXL0610

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4G1

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human LYVE-1 antibody

Catalog number (SKU) :

AXL0610

NCBI :

NP_006682

Description :

Lymphatic vascular endothelial hyaluronan receptor-1 (LYVE-1), a selective marker of the lymphatic endothelium, is a surface endocytic receptor for hyaluronan (HA), which is an extracellular glycosaminoglycan involved in cell adhesion and migration. HA is widely expressed on leukocytes, dendritic cells, and tumor cell, and is identified by searching expressed sequence tag (EST) databases for sequences homologous (41%) with the metastasis related CD44 molecules.

Alternative Names :

XLkD1(extracellular link domain containing 1), HAR, LYVE-1, CRSBP-1, lymphatic vessel endothelial hyaluronan receptor 1, extracellular link domain containing 1,

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Koukourakis MI. et al. (2006) J. Clin. Pathol. 58, 202-206.;; Chen L. et al. (2005) Invest. Ophthalmol Vis. Sci. 46, 4536-4540.;; Banerji S. et al. (1999) J. Cell Biol. 144, 789-801.

Abs Host :

Mouse

Isotype :

IgG2b kappa

Immunogen :

Recombinant human LYVE-1 (25-235 aa) purified from E. coli

Applications :

ELISA, WB, ICC/IF

IF Comment And Pic :

ICC/IF analysis of LYVE-1 in A549 cells. The cell was stained with AXL0610 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

A549 (lung carcinoma) cell lysate(40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human LYVE-1 antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

4G1

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Angiogenesis

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-G affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q9Y5Y7

Internal Search Terms :

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References with this Product :

Rodriguez-Laguna L, et al. Somatic activating mutations in PIK3CA cause generalized lymphatic anomaly. (J Exp Med. 2019){https://pubmed.ncbi.nlm.nih.gov/30591517/}

more info or order :

NKMAX product webpage