Recombinant human Serpin A1/alpha 1-Antitrypsin protein

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Serpin A1/alpha 1-Antitrypsin protein

catalog :

ATR0901

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Serpin A1/alpha 1-Antitrypsin protein

Domain :

25-418aa

Catalog number (SKU) :

ATR0901

NCBI :

NP_000286.2

Description :

Alpha 1 proteinase inhibitor (Antitrypsin) has a characteristic secondary structure of beta sheets and alpha helices. That is a serum glycoprotein synthesized in the liver. It acts as an elastase inhibitor, primarily inhibiting neutrophil elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. Also Increase in Antitrypsin occurs as an acute phase response to tissue necrosis and inflammation. Serum level of Antitrypsin is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis. Recombinant Antitrypsin protein was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

PI, A1A, AAT, PI1, A1AT, MGC9222, PRO2275, MGC23330, SERP1NA1, Alpha-1 antiproteinase, Serine proteinase inhibitor, Antitrypsin, Alpha 1 antiproteinase, Alpha 1 antitrypsin, alpha 1 AT, Alpha 1 protease inhibitor, alpha1 PI, MGC23330, alpha1 proteinase inhibitor, Clade A member 1, cysteine proteinase inhibitor, Serpin A1, Protease inhibitor 1, Serpin peptidase inhibitor clade A member 1, SerpinA1, Alpha-1 Antitrypsin, A1AT, serum trypsin inhibitor

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 10% glycerol, 1mM DTT, 2mM EDTA

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kolarich D., et al. (2006).Proteomics. 6(11):3369-80;; Wu Y., et al. (1991).Bioessays. 13(4):163-9;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Serology

Molecular Weight :

44.4 kDa (395aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MEDPQGDAAQ KTDTSHHDQD HPTFNKITPN LAEFAFSLYR QLAHQSNSTN IFFSPVSIAT AFAMLSLGTK ADTHDEILEG LNFNLTEIPE AQIHEGFQEL LRTLNQPDSQ LQLTTGNGLF LSEGLKLVDK FLEDVKKLYH SEAFTVNFGD TEEAKKQIND YVEKGTQGKI VDLVKELDRD TVFALVNYIF FKGKWERPFE VKDTEEEDFH VDQVTTVKVP MMKRLGMFNI QHCKKLSSWV LLMKYLGNAT AIFFLPDEGK LQHLENELTH DIITKFLENE DRRSASLHLP KLSITGTYDL KSVLGQLGIT KVFSNGADLS GVTEEAPLKL SKAVHKAVLT IDEKGTEAAG AMFLEAIPMS IPPEVKFNKP FVFLMIDQNT KSPLFMGKVV NPTQK

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P01009

Internal Search Terms :

Serpin A1, a1-Antitrypsin, PI, A1A, AAT, PI1, A1AT, MGC9222, PRO2275, MGC23330, SERP1NA1, Alpha-1 antiproteinase, Serine proteinase inhibitor, Antitrypsin, Alpha 1 antiproteinase, Alpha 1 antitrypsin, alpha 1 AT, Alpha 1 protease inhibitor, alpha1 PI, MGC23330, alpha1 proteinase inhibitor, Clade A member 1, cysteine proteinase inhibitor, Serpin A1, Protease inhibitor 1, Serpin peptidase inhibitor clade A member 1, SerpinA1, Alpha-1 Antitrypsin, A1AT, serum trypsin inhibitor,ATR0901-10ug,ATR0901-20ug,ATR0901-50ug,ATR0901-100ug,ATR0901-250ug,ATR0901-500ug,ATR0901-1mg,ATR0901-10,ATR0901-20,ATR0901-50,ATR0901-100,ATR0901-250,ATR0901-500,ATR0901-1

more info or order :

NKMAX product webpage