Recombinant human IL-7 protein | NKMAX ATGP4159 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-7 protein

catalog :

ATGP4159

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-7 protein

Domain :

26-177aa

Catalog number (SKU) :

ATGP4159

NCBI :

NP_000871.1

Description :

IL7, as known as interleukin-7 isoform 1, is a cytokine of the hemopoietin family that plays important roles in lymphocyte differentiation, proliferation, and survival. This protein is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by normal lymphocytes. It stimulates the proliferation of lymphoid progenitors and is important for proliferation during certain stages of B-cell maturation. IL7 and HGF form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes. Recombinant human IL7, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-7 isoform 1, IL7, IL-7, Il7, Interleukin-7

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Iolyeva M., et al. (2013) Blood 122:2271-2281.;; Younas M., et al. (2013) J. Immunol. 191:3161-3168.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using PHA-activated human Peripheral Blood Mononuclear Cells(PBMC). The ED50 range ≤ 8 ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

18.4 kDa (161aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human IL-7 stimulates cell proliferation of the PHA-activated human Peripheral Blood Mononuclear Cells(PBMC). The ED50 range ≤ 8 ng/ml.

Amino Acid Sequence :

DCDIEGK DGKQYESVLM VSIDQLLDSM KEIGSNCLNN EFNFFKRHIC DANKEGMFLF RAARKLRQFL KMNSTGDFDL HLLKVSEGTT ILLNCTGQVK GRKPAALGEA QPTKSLEENK SLKEQKKLND LCFLKRLLQE IKTCWNKILM GTKEH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P13232

Internal Search Terms :

ATGP4159-10ug, ATGP4159-20ug, ATGP4159-50ug, ATGP4159-100ug, ATGP4159-250ug, ATGP4159-500ug, ATGP4159-1mg, ATGP4159-010, ATGP4159-020, ATGP4159-050, ATGP4159-100, ATGP4159-250, ATGP4159-500, ATGP4159-01M, ATGP3442-10ug, ATGP3442-20ug, ATGP3442-50ug, ATGP3442-100ug, ATGP3442-250ug, ATGP3442-500ug, ATGP3442-1mg, ATGP3442-010, ATGP3442-020, ATGP3442-050, ATGP3442-100, ATGP3442-250, ATGP3442-500, ATGP3442-01M

more info or order :

NKMAX product webpage