Recombinant mouse RANK/TNFRSF11A protein | NKMAX ATGP4155 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse RANK/TNFRSF11A protein

catalog :

ATGP4155

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse RANK/TNFRSF11A protein

Domain :

31-214aa

Catalog number (SKU) :

ATGP4155

NCBI :

NP_033425.3

Description :

RANK, as known as Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A) is a member of the tumor necrosis factor receptor (TNFR) molecular sub-family. It is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It is associated with bone remodeling and repair, activation of NF-kappa B and c-jun N-terminal kinase, enhancement of T cell growth and dendritic cell function, immune cell function, lymph node development, thermal regulation, and mammary gland development. It is able to block TRANCE induced biological activity. Recombinant mouse RANK, fused to hlgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

TNF receptor superfamily member 11a, Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, Receptor activator of NF-KB, Familial expansile osteolysis, TRANCE receptor, RANK, CD265, FEO, ODFR, TRANCE-R, TNR11

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Anderson, D.M. et al. (1997) Nature 390, 175-179.;; Nakagawa, N. et al. (1998) Biochem. Biophys. Res. Commun. 245:395-400.;; Bharat B. Aggarwal. (2003) Nature 3, 745-756.;;

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Mouse RANKL/TNFSF11 (CAT# ATGP3915). The ED50 range ≤ 200 ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Mouse

Gene Category :

Immunology, Hormones & Cytokines

Molecular Weight :

47.5 kDa (426aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Mouse RANKL/TNFSF11 (CAT# ATGP3915) is coated at 1 ug/ml (100 ul/well) can bind Mouse RANK/TNFRSF11A. The ED50 range ≤ 200 ng/ml.

Amino Acid Sequence :

VTPPCTQ ERHYEHLGRC CSRCEPGKYL SSKCTPTSDS VCLPCGPDEY LDTWNEEDKC LLHKVCDAGK ALVAVDPGNH TAPRRCACTA GYHWNSDCEC CRRNTECAPG FGAQHPLQLN KDTVCTPCLL GFFSDVFSST DKCKPWTNCT LLGKLEAHQG TTESDVVCSS SMTLRRPPKE AQAYLPS

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

O35305

Internal Search Terms :

ATGP4155-10ug, ATGP4155-20ug, ATGP4155-50ug, ATGP4155-100ug, ATGP4155-250ug, ATGP4155-500ug, ATGP4155-1mg, ATGP4155-010, ATGP4155-020, ATGP4155-050, ATGP4155-100, ATGP4155-250, ATGP4155-500, ATGP4155-01M, ATGP3939-10ug, ATGP3939-20ug, ATGP3939-50ug, ATGP3939-100ug, ATGP3939-250ug, ATGP3939-500ug, ATGP3939-1mg, ATGP3939-010, ATGP3939-020, ATGP3939-050, ATGP3939-100, ATGP3939-250, ATGP3939-500, ATGP3939-01M

more info or order :

NKMAX product webpage