product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant Human Osteocrin protein
catalog :
ATGP4150
quantity :
10 ug
price :
160 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant Human Osteocrin protein
Domain :
28-133aa
Catalog number (SKU) :
ATGP4150
NCBI :
NP_937827.1
Description :
Osteocrin, also known as Musclin, shows a well conserved homology with members of the natriuretic peptide (NP) family. It is a secreted protein that is expressed in muscle and bone. Based on similarities with NPs, Osteocrin could interact with the NP clearance receptors, importantly increasing CNP which has been shown to stimulate endochondral ossification and elongate bones. It is represents a novel, unique vitamin D-regulated bone-specific. Recombinant human Osteocrin, fused to His-tag at C-terminus, was expressed in HEK 293 cell and purified by using conventional chromatography techniques.
Alternative Names :
Osteocrin, MUSCLIN, OSTN
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Thomas, G., et al, (2003) J. Biol. Chem. 278:50563–50571.;; Nishizawa H., et al, (2004) J Biol Chem. 279:19391-19395.;; Pierre Moffatt., et al, (2007) J Biol Chem. 282:36454-36462.
Purity :
> 95% by SDS-PAGE
Bioactivity Comment Only :
Measured by its binding ability in a functional ELISA with Human NPRC. The ED50 range ≤ 20 ng/ml.
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Human
Gene Category :
Stem cell
Molecular Weight :
12.5kDa (112aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Human NPRC is coated at 2 ug/ml (100 ul/well) can bind Human OSTN. The ED50 range ≤ 20 ng/ml.
Amino Acid Sequence :
VDVTTTEAFD SGVIDVQSTP TVREEKSATD LTAKLLLLDE LVSLENDVIE TKKKRSFSGF GSPLDRLSAG SVDHKGKQRK VVDHPKRRFG IPMDRIGRNR LSNSRG
Tag :
His-Tag
Expression System :
HEK293
Predicted nterm :
Val 19
Product Type Name :
Recombinant Protein
UniProt No. :
P61366
Internal Search Terms :
ATGP4150-10ug, ATGP4150-20ug, ATGP4150-50ug, ATGP4150-100ug, ATGP4150-250ug, ATGP4150-500ug, ATGP4150-1mg, ATGP4150, ATGP4150-020, ATGP4150-050, ATGP4150-100, ATGP4150-250, ATGP4150-500, ATGP4150-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.