Recombinant mouse EphA3 protein | NKMAX ATGP4148 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse EphA3 protein

catalog :

ATGP4148

quantity :

10 ug

price :

130 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse EphA3 protein

Domain :

21-541aa

Catalog number (SKU) :

ATGP4148

NCBI :

NP_034270.1

Description :

EphA3 is a protein-tyrosine kinase that belongs to the ephrin receptor subfamily. It has an extracellular region with a Cys-rich domain and two fibronectin type III repeats, and a single kinase domain. EPH and other EPH-related receptors are involved in various developmental processes, especially in the nervous system. EphA3 interacts with EFNB2 and EFNA5, and is expressed in the forebrain, retinal axons, some motor neurons in the spinal cord, and the heart during development. It regulates axonal guidance and organ formation. It is also found on some blood and solid tumor cells, and on astrocytes near injured nerve tissue. Recombinant mouse EphA3, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Alternative Names :

ephrin type-A receptor 3, ephrin type-A receptor 3 isoform1, receptor protein-tyrosine kinase, EPH-like kinase 4, tyrosine-protein kinase TYRO4, tyrosine-protein kinase receptor ETK1, Eph receptor A3, AW492086, Cek4, EK4, End3, ETK1, Hek, Hek4, Mek4, Tyro4

Concentration :

1mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kudo, C. et al. (2005) J. Comp. Neurol. 487:255-269.;; Kilpatrick, T.J. et al. (1996) Mol. Cell. Neurosci. 7:62-74.;; Stephen, L.J. et al. (2007) Dev. Biol. 302:66-79.;; Merlos-Suarez, A. and E. Batlle (2008) Curr. Opin. Cell Biol. 20:194-200.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human EFNA5 (CAT# ATGP4147).

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Mouse

Gene Category :

Angiogenesis, Cardiovascular

Molecular Weight :

59.5kDa (527aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Mouse EphA3 (CAT# ATGP4148) is coated at 2 ug/ml (100 ul/well) can bind Human EFNA5 (CAT# ATGP4147) in a Functional ELISA assay.

Amino Acid Sequence :

ELSPQPSNEV NLLDSKTIQG ELGWISYPSH GWEEISGVDE HYTPIRTYQV CNVMDHSQNN WLRTNWVPRN SAQKIYVELK FTLRDCNSIP LVLGTCKETF NLYYMESDDD HGVKFREHQF TKIDTIAADE SFTQMDLGDR ILKLNTEIRE VGPVNKKGFY LAFQDVGACV ALVSVRVYFK KCPFTVKNLA MFPDTVPMDS QSLVEVRGSC VNNSKEEDPP RMYCSTEGEW LVPIGKCTCN AGYEERGFIC QACRPGFYKA SDGAAKCAKC PPHSSTQEDG SMNCRCENNY FRAEKDPPSM ACTRPPSAPR NVISNINETS VILDWSWPLD TGGRKDITFN IICKKCGWNV RQCEPCSPNV RFLPRQLGLT NTTVTVTDLL AHTNYTFEID AVNGVSELSS PPRQYAAVSI TTNQAAPSPV MTIKKDRTSR NSISLSWQEP EHPNGIILDY EVKYYEKQEQ ETSYTILRAR GTNVTISSLK PDTTYVFQIR ARTAAGYGTN SRKFEFETSP DSFSISGENS H

Tag :

His-Tag

Expression System :

HEK293

Predicted nterm :

Glu 21

Product Type Name :

Recombinant Protein

UniProt No. :

Q8BRB1

Internal Search Terms :

ATGP4148-10ug, ATGP4148-20ug, ATGP4148-50ug, ATGP4148-100ug, ATGP4148-250ug, ATGP4148-500ug, ATGP4148-1mg, ATGP4148-010, ATGP4148-020, ATGP4148-050, ATGP4148-100, ATGP4148-250, ATGP4148-500, ATGP4148-01M

more info or order :

NKMAX product webpage