Recombinant human PIGF-2 protein | NKMAX ATGP4143 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PIGF-2 protein

catalog :

ATGP4143

quantity :

10 ug

price :

160 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PIGF-2 protein

Domain :

19-170aa

Catalog number (SKU) :

ATGP4143

NCBI :

NP_002623.2

Description :

PIGF-2, as know as placenta growth factor, is a member of the VEGF sub-family that a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. It is ultimately associated with angiogenesis. Specifically, it plays a role in trophoblast growth and differentiation. Also it is a potential biomarker for preeclampsia, a condition in which blood vessels in the placenta are too narrow, resulting in high blood pressure. Under normal physiologic conditions, it is also expressed at a low level in other organs including the heart, lung, thyroid, and skeletal muscle. Recombinant human PIGF-2, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.

Alternative Names :

placental growth factor, placenta growth factor isoform 1, PGF, D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760

Concentration :

0.5mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Asma Khalil., et al, (2008) PLoS One. 3:e2766.;; Khurana R., et al, (2005) Circulation. 111:2828-2836.

Purity :

> 90% by SDS - PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human VEGFR1/Flt-1 (CAT# ATGP4101).

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Angiogenesis, Cardiovascular

Molecular Weight :

18.1kDa (158aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human PIGF-2 is coated at 2 ug/ml (100 ul/well) can bind Human VEGFR1/Flt-1 (CAT# ATGP4101) in a Functional ELISA assay.

Amino Acid Sequence :

LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR

Tag :

His-Tag

Expression System :

HEK293

Predicted nterm :

Leu19

Product Type Name :

Recombinant Protein

UniProt No. :

P49763-3

Internal Search Terms :

ATGP4143-10ug, ATGP4143-20ug, ATGP4143-50ug, ATGP4143-100ug, ATGP4143-250ug, ATGP4143-500ug, ATGP4143-1mg, ATGP4143-010, ATGP4143-020, ATGP4143-050, ATGP4143-100, ATGP4143-250, ATGP4143-500, ATGP4143-01M

more info or order :

NKMAX product webpage