Recombinant human Crystallin alpha B/CRYAB protein | NKMAX ATGP4137 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Crystallin alpha B/CRYAB protein

catalog :

ATGP4137

quantity :

10 ug

price :

74 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Crystallin alpha B/CRYAB protein

Domain :

1-175aa

Catalog number (SKU) :

ATGP4137

NCBI :

NP_001876.1

Description :

Alpha crystallins are composed of two gene products ; alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-B is expressed widely in many tissues and organs and occurs in many neurological diseases.

Alternative Names :

CRYAB, CRYA2, CRYAB (Crystallin alpha B), Rosenthal fiber component, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY-REN-27, Alpha crystallin B chain, AACRYA, Alpha(B) crystallin, Crystallin alpha polypeptide 2, CTPP 2, CTPP2, Heat shock 20 kD like protein, Heat shock protein beta 5, NY REN 27 antigen, Renal carcinoma antigen NY REN 27

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Hasan, A., et al.(2002) Biochemistry 41(52) 15876-15882;; Kamradt,M.C. , et al(2002) J. Biol.Chem. 277(41) 38731-38736 ;; Reddy, G.B., et al(2002) FEBS lett. 522(1-3) 59-64 ;; Ito, H., et al(2002) J.Biochem.131(4) 593-603;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Heat Shock Proteins

Molecular Weight :

21.2 kDa (183aa)

Amino Acid Sequence :

MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFPT STSLSPFYLR PPSFLRAPSW FDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT AAPKK

Tag :

His-Tag

Expression System :

E.coli

Predicted nterm :

Recombinant Protein

UniProt No. :

P02511

Internal Search Terms :

AACRYA, Alpha crystallin B chain, Alpha(B) crystallin, Alpha-crystallin B chain, Crya2, Crya-2, Cryab, CRYAB (Crystallin alpha B), Crystallin alpha B, Crystallin alpha polypeptide 2, CTPP2, Heat shock 20 kD like protein, Heat shock protein beta 5, Heat shock protein beta-5, HspB5, NY REN 27 antigen, Renal carcinoma antigen NY-REN-27, Rosenthal fiber component, ATGP4137-10ug,ATGP4137-20ug,ATGP4137-50ug,ATGP4137-100ug,ATGP4137-250ug,ATGP4137-500ug,ATGP4137-1mg,ATGP4137-10,ATGP4137-20,ATGP4137-50,ATGP4137-100,ATGP4137-250,ATGP4137-500,ATGP4137-1

more info or order :

NKMAX product webpage