Recombinant mouse MMP-9 protein | NKMAX ATGP4127 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse MMP-9 protein

catalog :

ATGP4127

quantity :

10 ug

price :

160 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse MMP-9 protein

Domain :

20-730aa

Catalog number (SKU) :

ATGP4127

NCBI :

NP_038627.1

Description :

MMP-9, also known matrix metalloproteinase-9, is one of the matrix metalloproteinases superfamily which is zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. It degrades many substrates such as gelatin, collagens, elastin and proteoglycan core protein which appears to be involved in invasive ability. This protein also plays an essential role in leukocyte migration and in bone osteoclastic resorption. It plays an important role in angiogenesis and neovascularization and so appears to be involved in the remodeling associated with malignant glioma neovascularization. Recombinant mouse MMP-9 protein, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Alternative Names :

Matrix metalloproteinase-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB, Mmp9, MANDP2, AW743869, B/MMP, B/MMP9, Clg4, Clg4b, Gel B, MMP-9, pro-MMP-9

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl (pH 7.5) containing 1mM CaCl2, 100mM NaCl, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lee YD., et al, (2014) BMB Rep. 47:262-267.;; Matin S., et al, (2018) Int J Chron Obstruct Pulmon Dis. 13:1449-1454.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is >1,500 pmol/min/ug, and is defined as the amount of enzyme that cleaves 1pmol of Mca-PLGL-Dpa-AR-NH2 per minute at pH 7.5 at 25C.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Mouse

Gene Category :

Angiogenesis, Cardiovascular, Adhesion & Movement

Molecular Weight :

79.3kDa (717aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Specific activity is >1,500 pmol/min/ug, and is defined as the amount of enzyme that cleaves 1pmol of Mca-PLGL-Dpa-AR-NH2 per minute at pH 7.5 at 25C.

Amino Acid Sequence :

APYQRQPTFV VFPKDLKTSN LTDTQLAEAY LYRYGYTRAA QMMGEKQSLR PALLMLQKQL SLPQTGELDS QTLKAIRTPR CGVPDVGRFQ TFKGLKWDHH NITYWIQNYS EDLPRDMIDD AFARAFAVWG EVAPLTFTRV YGPEADIVIQ FGVAEHGDGY PFDGKDGLLA HAFPPGAGVQ GDAHFDDDEL WSLGKGVVIP TYYGNSNGAP CHFPFTFEGR SYSACTTDGR NDGTPWCSTT ADYDKDGKFG FCPSERLYTE HGNGEGKPCV FPFIFEGRSY SACTTKGRSD GYRWCATTAN YDQDKLYGFC PTRVDATVVG GNSAGELCVF PFVFLGKQYS SCTSDGRRDG RLWCATTSNF DTDKKWGFCP DQGYSLFLVA AHEFGHALGL DHSSVPEALM YPLYSYLEGF PLNKDDIDGI QYLYGRGSKP DPRPPATTTT EPQPTAPPTM CPTIPPTAYP TVGPTVGPTG APSPGPTSSP SPGPTGAPSP GPTAPPTAGS SEASTESLSP ADNPCNVDVF DAIAEIQGAL HFFKDGWYWK FLNHRGSPLQ GPFLTARTWP ALPATLDSAF EDPQTKRVFF FSGRQMWVYT GKTVLGPRSL DKLGLGPEVT HVSGLLPRRL GKALLFSKGR VWRFDLKSQK VDPQSVIRVD KEFSGVPWNS HDIFQYQDKA YFCHGKFFWR VSFQNEVNKV DHEVNQVDDV GYVTYDLLQC P

Tag :

His-Tag

Expression System :

HEK293

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P41245

Internal Search Terms :

ATGP4127-10ug, ATGP4127-20ug, ATGP4127-50ug, ATGP4127-100ug, ATGP4127-250ug, ATGP4127-500ug, ATGP4127-1mg, ATGP4127-010, ATGP4127-020, ATGP4127-050, ATGP4127-100, ATGP4127-250, ATGP4127-500, ATGP4127-01M,ATGP4087-10ug, ATGP4087-20ug, ATGP4087-50ug, ATGP4087-100ug, ATGP4087-250ug, ATGP4087-500ug, ATGP4087-1mg, ATGP4087-010, ATGP4087-020, ATGP4087-050, ATGP4087-100, ATGP4087-250, ATGP4087-500, ATGP4087-01M

more info or order :

NKMAX product webpage