product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Lactate Dehydrogenase A/LDHA protein
catalog :
ATGP4118
quantity :
10 ug
price :
120 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Lactate Dehydrogenase A/LDHA protein
Domain :
1-332aa
Catalog number (SKU) :
ATGP4118
NCBI :
NP_034829
Description :
Ldha, also known as L-lactate dehydrogenase A chain isoform 1, is a member of the LDH/MDH superfamily and LDH family. It catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. This protein is found predominantly in muscle tissue. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It plays an important role in the development, invasion and metastasis of malignancies. Recombinant mouse Ldha, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
L-lactate dehydrogenase A chain isoform 1, LDH muscle subunit (LDH-M), Ldha, 17R2, Ldh1, Ldhm, LDH-A, LDH muscle smb
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Rong Y., et al. (2013) Tumour Biol. 34(3):1523-1530.;; Merkle S., et al. (1992) Genetics. 131(2):413-421.
Purity :
> 95% by SDS-PAGE
Bioactivity Comment Only :
Specific activity is > 250unit/mg, and is defined as the Amount of enzyme that convert 1.0 umole of pyruvate to L-lactate and per minute at pH 7.5 at 37℃.
Applications :
SDS-PAGE, Enzyme Activity
Antigen Species :
Mouse
Gene Category :
Signal Transduction, Metabolism
Additional Comment Only :
ATGP3341 has been replaced with a catalog number ATGP4118.
Molecular Weight :
37.5 kDa (340aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Specific activity is > 250unit/mg, and is defined as the Amount of enzyme that convert 1.0 umole of pyruvate to L-lactate and per minute at pH 7.5 at 37℃.
Amino Acid Sequence :
MATLKDQLIV NLLKEEQAPQ NKITVVGVGA VGMACAISIL MKDLADELAL VDVMEDKLKG EMMDLQHGSL FLKTPKIVSS KDYCVTANSK LVIITAGARQ QEGESRLNLV QRNVNIFKFI IPNIVKYSPH CKLLIVSNPV DILTYVAWKI SGFPKNRVIG SGCNLDSARF RYLMGERLGV HALSCHGWVL GEHGDSSVPV WSGVNVAGVS LKSLNPELGT DADKEQWKEV HKQVVDSAYE VIKLKGYTSW AIGLSVADLA ESIMKNLRRV HPISTMIKGL YGINEDVFLS VPCILGQNGI SDVVKVTLTP EEEARLKKSA DTLWGIQKEL QF
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Met1
Product Type Name :
Recombinant Protein
UniProt No. :
P06151
Internal Search Terms :
ATGP4118-10ug, ATGP4118-20ug, ATGP4118-50ug, ATGP4118-100ug, ATGP4118-250ug, ATGP4118-500ug, ATGP4118-1mg, ATGP4118-010, ATGP4118-020, ATGP4118-050, ATGP4118-100, ATGP4118-250, ATGP4118-500, ATGP4118-01M,ATGP3341-10ug, ATGP3341-20ug, ATGP3341-50ug, ATGP3341-100ug, ATGP3341-250ug, ATGP3341-500ug, ATGP3341-1mg, ATGP3341-010, ATGP3341-020, ATGP3341-050, ATGP3341-100, ATGP3341-250, ATGP3341-500, ATGP3341-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.