product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human GP1BB protein
catalog :
ATGP4114
quantity :
10 ug
price :
150 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human GP1BB protein
Domain :
26-147aa
Catalog number (SKU) :
ATGP4114
NCBI :
NP_000398.1
Description :
GP1BB, also known as glycoprotein Ib platelet subunit beta/CD42c, is a member of platelet receptor family. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. This complex is composed of GPIb alpha attached to GPIb beta and non-covalently complexed with GPIX and GPV. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in GP1BB have been associated with Bernard–Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. Recombinant human GP1BB, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Alternative Names :
glycoprotein Ib platelet subunit beta, BDPLT1, BS, CD42C, GPIBB, GPIbbeta, Antigen CD42b-beta, GP-Ib beta, GPIb-beta, GPIbB, Platelet glycoprotein Ib beta chain
Concentration :
0.25mg/ml (determined by Absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Kenny D, et al. (2002) Blood. 99:4428-4433.;; Clemetson KJ, et al. (2008) Thromb Haemost. 99:473-479.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
14kDa (131aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
CPAPCSC AGTLVDCGRR GLTWASLPTA FPVDTTELVL TGNNLTALPP GLLDALPALR TAHLGANPWR CDCRLVPLRA WLAGRPERAP YRDLRCVAPP ALRGRLLPYL AEDELRAACA PGPLC
Tag :
His-Tag
Expression System :
HEK293
Predicted nterm :
Asp
Product Type Name :
Recombinant Protein
UniProt No. :
P13224
Internal Search Terms :
ATGP4114-10ug, ATGP4114-20ug, ATGP4114-50ug, ATGP4114-100ug, ATGP4114-250ug, ATGP4114-500ug, ATGP4114-1mg, ATGP4114-010, ATGP4114-020, ATGP4114-050, ATGP4114-100, ATGP4114-250, ATGP4114-500, ATGP4114-01M
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.