Recombinant human POR protein | NKMAX ATGP4107 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human POR protein

catalog :

ATGP4107

quantity :

10 ug

price :

160 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human POR protein

Domain :

43-677aa

Catalog number (SKU) :

ATGP4107

NCBI :

NP_001382342.1

Description :

POR, also known as NADPH--cytochrome P450 reductase, is a flavoprotein that donates electrons to all microsomal P450 enzymes. POR is localized to the endoplasmic reticulum, where it is also able to transfer electrons to heme oxygenase and cytochrome b5. It is structurally related to two separate flavoprotein families, ferredoxin nucleotide reductase and flavodoxin. Recombinant human POR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

NADPH--cytochrome P450 reductase, NADPH--cytochrome P450 reductase, CPR, CYPOR, P450R

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Shen A L,et al. (1989). J Biol Chem. 264:7584-7589.;; Haniju M,et al. (1989). Biochemistry. 28:8639-8645.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 1,500 pmol/min/ug, and is defined as the amount of enzyme that catalyze the reduction of 1.0 pmole cytochrome C by NADPH per minute at pH8.0 at 25C.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

73kDa (642aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Specific activity is > 1,500 pmol/min/ug, and is defined as the amount of enzyme that catalyze the reduction of 1.0 pmole cytochrome C by NADPH per minute at pH8.0 at 25C.

Amino Acid Sequence :

MLFRKKKEEV PEFTKIQTLT SSVRESSFVE KMKKTGRNII VFYGSQTGTA EEFANRLSKD AHRYGMRGMS ADPEEYDLAD LSSLPEIDNA LVVFCMATYG EGDPTDNAQD FYDWLQETDV DLSGVKFAVF GLGNKTYEHF NAMGKYVDKR LEQLGAQRIF ELGLGDDDGN LEEDFITWRE QFWPAVCEHF GVEATGEESS IRQYELVVHT DIDAAKVYMG EMGRLKSYEN QKPPFDAKNP FLAAVTTNRK LNQGTERHLM HLELDISDSK IRYESGDHVA VYPANDSALV NQLGKILGAD LDVVMSLNNL DEESNKKHPF PCPTSYRTAL TYYLDITNPP RTNVLYELAQ YASEPSEQEL LRKMASSSGE GKELYLSWVV EARRHILAIL QDCPSLRPPI DHLCELLPRL QARYYSIASS SKVHPNSVHI CAVVVEYETK AGRINKGVAT NWLRAKEPAG ENGGRALVPM FVRKSQFRLP FKATTPVIMV GPGTGVAPFI GFIQERAWLR QQGKEVGETL LYYGCRRSDE DYLYREELAQ FHRDGALTQL NVAFSREQSH KVYVQHLLKQ DREHLWKLIE GGAHIYVCGD ARNMARDVQN TFYDIVAELG AMEHAQAVDY IKKLMTKGRY SLDVWS

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Met

Product Type Name :

Recombinant Protein

UniProt No. :

P16435

Internal Search Terms :

ATGP4107-10ug,ATGP4107-20ug,ATGP4107-50ug,ATGP4107-100ug,ATGP4107-250ug,ATGP4107-500ug,ATGP4107-1mg,ATGP4107-10,ATGP4107-20,ATGP4107-50,ATGP4107-100,ATGP4107-250,ATGP4107-500,ATGP4107-1

more info or order :

NKMAX product webpage