Recombinant human CD16a/FCGR3A protein | NKMAX ATGP4102 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD16a/FCGR3A protein

catalog :

ATGP4102

quantity :

10 ug

price :

132 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD16a/FCGR3A protein

Domain :

18-208aa

Catalog number (SKU) :

ATGP4102

NCBI :

NP_001121065.1

Description :

FCGR3A, also known as low affinity immunoglobulin gamma Fc region receptor III-A, is a multifunctional, low or intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is expressed on human NK cells as an integral membrane glycoprotein anchored through a transmembrane peptide. It mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Recombinant human FCGR3A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Low affinity immunoglobulin gamma Fc region receptor III-A,low affinity immunoglobulin gamma Fc region receptor III-A isoform c, IgG Fc receptor III-A, CD16-II, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcgammaRIIIA, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, FCGRIII, IGFR3, IMD20, CD16

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ravetch JV., et al. (1989) J Exp Med. 170:481-497.;; Ferrara C., et al. (2011) Proc Natl Acad Sci U S A. 108:12669-12674.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human IgG1 Fc (CAT# ATGP4094).

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology

Additional Comment Only :

ATGP3449 has been replaced with a catalog number ATGP4102.

Molecular Weight :

22.8 kDa (200aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human Fc gamma RIIIA/CD16a is coated at 10 ug/ml (100 ul/well) can bind Human IgG1 Fc (CAT# ATGP4094) in a functional ELISA assay.

Amino Acid Sequence :

MRTEDLP KAVVFLEPQW YRVLEKDSVT LKCQGAYSPE DNSTQWFHNE SLISSQASSY FIDAATVDDS GEYRCQTNLS TLSDPVQLEV HIGWLLLQAP RWVFKEEDPI HLRCHSWKNT ALHKVTYLQN GKGRKYFHHN SDFYIPKATL KDSGSYFCRG LFGSKNVSSE TVNITITQGL AVSTISSFFP PGYQ

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P08637

Internal Search Terms :

ATGP4102-10ug,ATGP4102-20ug,ATGP4102-50ug,ATGP4102-100ug,ATGP4102-250ug,ATGP4102-500ug,ATGP4102-1mg,ATGP4102-10,ATGP4102-20,ATGP4102-50,ATGP4102-100,ATGP4102-250,ATGP4102-500,ATGP4102-1, ATGP3449-10ug,ATGP3449-20ug,ATGP3449-50ug,ATGP3449-100ug,ATGP3449-250ug,ATGP3449-500ug,ATGP3449-1mg,ATGP3449-10,ATGP3449-20,ATGP3449-50,ATGP3449-100,ATGP3449-250,ATGP3449-500,ATGP3449-1

more info or order :

NKMAX product webpage