Recombinant human F-spondin/SPON1 protein | NKMAX ATGP4083 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human F-spondin/SPON1 protein

catalog :

ATGP4083

quantity :

10 ug

price :

140 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human F-spondin/SPON1 protein

Domain :

29-807aa

Catalog number (SKU) :

ATGP4083

NCBI :

NP_006099.2

Description :

SPON1, also known as F-Spondin, is a member of a sub-group of TSR(thrombospondin) molecules. It is a cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurities in vitro. This protein may contribute to the growth and guidance of axons. SPON1 is also major factor for vascular smooth muscle cell. It shows highest expression in lung and lowest expression in pancreas, skeletal muscle and ovary. This protein binds to the central extracellular of APP and inhibits beta-secretase cleavage of APP. Recombinant human SPON1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Alternative Names :

f-spondin, VSGP/F-spondin, spondin-1, SPON1, vascular smoth muscle cell growth-promoting factor

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Heximer S., et al, (2007) Circ Res. 100:940-942.;; Carrillo GL, et al, (2018) Front Neural Circuits. 12:13.;; Park SY, et al, (2020) Cells. 9:1275.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Angiogenesis, Cardiovascular

Molecular Weight :

88.9kDa (785aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

FSDETLDKVP KSEGYCSRIL RAQGTRREGY TEFSLRVEGD PDFYKPGTSY RVTLSAAPPS YFRGFTLIAL RENREGDKEE DHAGTFQIID EEETQFMSNC PVAVTESTPR RRTRIQVFWI APPAGTGCVI LKASIVQKRI IYFQDEGSLT KKLCEQDSTF DGVTDKPILD CCACGTAKYR LTFYGNWSEK THPKDYPRRA NHWSAIIGGS HSKNYVLWEY GGYASEGVKQ VAELGSPVKM EEEIRQQSDE VLTVIKAKAQ WPAWQPLNVR AAPSAEFSVD RTRHLMSFLT MMGPSPDWNV GLSAEDLCTK ECGWVQKVVQ DLIPWDAGTD SGVTYESPNK PTIPQEKIRP LTSLDHPQSP FYDPEGGSIT QVARVVIERI ARKGEQCNIV PDNVDDIVAD LAPEEKDEDD TPETCIYSNW SPWSACSSST CDKGKRMRQR MLKAQLDLSV PCPDTQDFQP CMGPGCSDED GSTCTMSEWI TWSPCSISCG MGMRSRERYV KQFPEDGSVC TLPTEETEKC TVNEECSPSS CLMTEWGEWD ECSATCGMGM KKRHRMIKMN PADGSMCKAE TSQAEKCMMP ECHTIPCLLS PWSEWSDCSV TCGKGMRTRQ RMLKSLAELG DCNEDLEQVE KCMLPECPID CELTEWSQWS ECNKSCGKGH VIRTRMIQME PQFGGAPCPE TVQRKKCRIR KCLRNPSIQK LRWREARESR RSEQLKEESE GEQFPGCRMR PWTAWSECTK LCGGGIQERY MTVKKRFKSS QFTSCKDKKE IRACNVHPC

Tag :

His-Tag

Expression System :

HEK293

Predicted nterm :

Phe29

Product Type Name :

Recombinant Protein

UniProt No. :

Q9HCB6

Internal Search Terms :

ATGP4083-10ug,ATGP4083-20ug,ATGP4083-50ug,ATGP4083-100ug,ATGP4083-250ug,ATGP4083-500ug,ATGP4083-1mg,ATGP4083-10,ATGP4083-20,ATGP4083-50,ATGP4083-100,ATGP4083-250,ATGP4083-500,ATGP4083-1

more info or order :

NKMAX product webpage