Recombinant human Angiopoietin-like 7/ANGPTL7 protein | NKMAX ATGP4082 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Angiopoietin-like 7/ANGPTL7 protein

catalog :

ATGP4082

quantity :

10 ug

price :

110 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Angiopoietin-like 7/ANGPTL7 protein

Domain :

27-346aa

Catalog number (SKU) :

ATGP4082

NCBI :

NP_066969.1

Description :

Angiopoietin-like 7, also known as Angiopoietin-related protein 7, is a member of angiopoietin-like (ANGPTL) family. Angiopoietin-like 7 have been shown to be involved in blood vessel formation or neovascularization in several models. When overexpressed in tumor cells it promotes collagen and proteoglycan deposition but inhibits tumor xenograft progression and tumor angiogenesis. It is also expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Overexpression of ANGPTL7 increases collagen expression. Thus, it could have a pathogenic role in glaucoma, and may serve as a potential therapeutic target. Recombinant human Angiopoietin-like 7, fused to hIgG-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Alternative Names :

Angiopoietin like 7, AngX, CDT6, Angiopoietin-related protein 7, ANGPTL7

Concentration :

0.25mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kuchtey, J., et al, (2008) Invest. Opthalmol. Visual Sci. 49:3438-3448. ;; Oike, Y., et al, (2009) Invest. Circ. J. 73:2192. ;;

Purity :

> 90% by SDS - PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

63.2kDa (553aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QKLSKHKTPA QPQLKAANCC EEVKELKAQV ANLSSLLSEL NKKQERDWVS VVMQVMELES NSKRMESRLT DAESKYSEMN NQIDIMQLQA AQTVTQTSAD AIYDCSSLYQ KNYRISGVYK LPPDDFLGSP ELEVFCDMET SGGGWTIIQR RKSGLVSFYR DWKQYKQGFG SIRGDFWLGN EHIHRLSRQP TRLRVEMEDW EGNLRYAEYS HFVLGNELNS YRLFLGNYTG NVGNDALQYH NNTAFSTKDK DNDNCLDKCA QLRKGGYWYN CCTDSNLNGV YYRLGEHNKH LDGITWYGWH GSTYSLKRVE MKIRPEDFKP

Tag :

hIgG-Tag

Expression System :

HEK293

Predicted nterm :

Gln 27

Product Type Name :

Recombinant Protein

UniProt No. :

O43827

Internal Search Terms :

angiopoietin like7, angiopoietin like 7, Angiopoietin like factor, Angiopoietin-like factor; Angiopoietin-like Protein 7, angiopoietin-related protein 7, ANGPTL7, AngX, CDT6, Cornea-derived transcript 6 protein, dJ647M16.1, ATGP4082-10ug, ATGP4082-20ug, ATGP4082-50ug, ATGP4082-100ug, ATGP4082-250ug, ATGP4082-500ug, ATGP4082-1mg, ATGP4082-010, ATGP4082-020, ATGP4082-050, ATGP4082-100, ATGP4082-250, ATGP4082-500, ATGP4082-01M

more info or order :

NKMAX product webpage