Recombinant human PKC iota protein | NKMAX ATGP4081 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PKC iota protein

catalog :

ATGP4081

quantity :

10 ug

price :

140 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PKC iota protein

Domain :

1-596aa

Catalog number (SKU) :

ATGP4081

NCBI :

NP_002731.4

Description :

PKC iota, also known as Protein Kinase C iota, is a member of serine/threonine protein kinases family. It play a key regulatory role in a number of cellular functions including cell growth and differentiation, hormone secretion, and gene expression. It is involved in cell polarization processes and the formation of epithelial tight junctions. This protein kinase is calcium-independent and phospholipid-dependent. It is also implicated in the activation of several signaling pathways including Ras, c-Src and NF-kappa-B pathways. Recombinant human PKC iota, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Alternative Names :

DXS1179E, nPKC-iota, PKCI, aPKC-lambda/iota, PRKC-lambda/iota, Protein kinase C iota type, Atypical protein kinase C-lambda/iota, PRKCL, Protein Kinase C iota, PRKCI

Concentration :

0.5mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Dey A et al, (2021) Cell Signal. 77:109819.;; Li HS et al, (2019) J Neurosci. 39:5773-5793.

Purity :

> 80% by SDS - PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

69kDa(602aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MPTQRDSSTM SHTVAGGGSG DHSHQVRVKA YYRGDIMITH FEPSISFEGL CNEVRDMCSF DNEQLFTMKW IDEEGDPCTV SSQLELEEAF RLYELNKDSE LLIHVFPCVP ERPGMPCPGE DKSIYRRGAR RWRKLYCANG HTFQAKRFNR RAHCAICTDR IWGLGRQGYK CINCKLLVHK KCHKLVTIEC GRHSLPQEPV MPMDQSSMHS DHAQTVIPYN PSSHESLDQV GEEKEAMNTR ESGKASSSLG LQDFDLLRVI GRGSYAKVLL VRLKKTDRIY AMKVVKKELV NDDEDIDWVQ TEKHVFEQAS NHPFLVGLHS CFQTESRLFF VIEYVNGGDL MFHMQRQRKL PEEHARFYSA EISLALNYLH ERGIIYRDLK LDNVLLDSEG HIKLTDYGMC KEGLRPGDTT STFCGTPNYI APEILRGEDY GFSVDWWALG VLMFEMMAGR SPFDIVGSSD NPDQNTEDYL FQVILEKQIR IPRSLSVKAA SVLKSFLNKD PKERLGCHPQ TGFADIQGHP FFRNVDWDMM EQKQVVPPFK PNISGEFGLD NFDSQFTNEP VQLTPDDDDI VRKIDQSEFE GFEYINPLLM SAEECV

Tag :

His-Tag

Expression System :

HEK293

Predicted nterm :

Met 1

Product Type Name :

Recombinant Protein

UniProt No. :

P41743

Internal Search Terms :

ATGP4081-10ug,ATGP4081-20ug,ATGP4081-50ug,ATGP4081-100ug,ATGP4081-250ug,ATGP4081-500ug,ATGP4081-1mg,ATGP4081-10,ATGP4081-20,ATGP4081-50,ATGP4081-100,ATGP4081-250,ATGP4081-500,ATGP4081-1

more info or order :

NKMAX product webpage