product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human IL-18R beta/IL18RAP protein
catalog :
ATGP4073
quantity :
10 ug
price :
78 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human IL-18R beta/IL18RAP protein
Domain :
20-356aa
Catalog number (SKU) :
ATGP4073
NCBI :
NP_003844.1
Description :
IL-18 R beta/IL-1 R7, also known as interleukin-18 receptor accessory protein, is a member of the IL-1 family of cytokines that has multiple immunoregulatory functions. It does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. IL18R1 and IL18RAP polymorphisms have been found associated with diseases such as schizophrenia, HSV1 seropositivity and atopic asthma. Recombinant human IL-18 R beta/IL-1 R7 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
ACPL, CD218 antigen-like family member B, CD218b, CDw218b, IL-18 receptor accessory protein, IL-18RAcP, IL18RAP, IL18RB, IL18Rbeta, IL-1R accessory protein-like, IL-1R7, IL-1RAcPL, Interleukin-1 receptor 7, Interleukin-18 receptor accessory protein, Interleukin-18 receptor accessory protein isoform 1, Interleukin-18 receptor beta
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Cheung H., et al, (2005) J Immunol. 174:5351-5357.;; Chandrasekar B., et al, (2003) Biochem Biophys Res Commun. 303:1152-1158.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
65.4 kDa (576aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
FNISGCSTKK LLWTYSTRSE EEFVLFCDLP EPQKSHFCHR NRLSPKQVPE HLPFMGSNDL SDVQWYQQPS NGDPLEDIRK SYPHIIQDKC TLHFLTPGVN NSGSYICRPK MIKSPYDVAC CVKMILEVKP QTNASCEYSA SHKQDLLLGS TGSISCPSLS CQSDAQSPAV TWYKNGKLLS VERSNRIVVD EVYDYHQGTY VCDYTQSDTV SSWTVRAVVQ VRTIVGDTKL KPDILDPVED TLEVELGKPL TISCKARFGF ERVFNPVIKW YIKDSDLEWE VSVPEAKSIK STLKDEIIER NIILEKVTQR DLRRKFVCFV QNSIGNTTQS VQLKEKR
Tag :
hIgG-His-Tag
Expression System :
Baculovirus
Predicted nterm :
Phe 20
Product Type Name :
Recombinant Protein
UniProt No. :
O95256
Internal Search Terms :
ACPL, CD218 antigen-like family member B, CD218b, CDw218b, IL-18 receptor accessory protein, IL-18RAcP, IL18RAP, IL18RB, IL18Rbeta, IL-18R-beta, IL-1R accessory protein-like, IL-1R7, IL-1R-7, IL-1RAcPL, Interleukin-1 receptor 7, Interleukin-18 receptor accessory protein, Interleukin-18 receptor accessory protein isoform 1, Interleukin-18 receptor beta, ATGP4073-10ug, ATGP4073-20ug, ATGP4073-50ug, ATGP4073-100ug, ATGP4073-250ug, ATGP4073-500ug, ATGP4073-1mg, ATGP4073-010, ATGP4073-020, ATGP4073-050, ATGP4073-100, ATGP4073-250, ATGP4073-500, ATGP4073-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.