product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse DKK1 protein
catalog :
ATGP4071
quantity :
10 ug
price :
120 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse DKK1 protein
Domain :
32-272aa
Catalog number (SKU) :
ATGP4071
NCBI :
NP_034181.2
Description :
Dkk-1, also known as Dickkopf-related protein 1, is a member of the Dkk protein family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Because of its antagonistic effects on the Wnt signaling pathway, it is believed that Dkk-1 is a common marker for neuronal death in neurodegenerative diseases like Alzheimer’s. Elevated level of Dkk-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. Recombinant mouse Dkk-1, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.
Alternative Names :
mDkk-1, Dkk-1, Dickkopf-related protein 1, Dickkopf-1, Dickkopf WNT signaling pathway inhibitor 1
Concentration :
0.25mg/ml (determined by Absorbance at 280nm)
Formulation :
Liquid in. 50mM MES buffer (pH 6.5) containing 30% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Krupnik, V.E. et al. (1999) Gene 238:301-13.;; Nusse, R. et al. (2001) Nature 411:255-6.;; Mao, J. et al. (2001) Mol. Cell 7:801-9.
Purity :
> 95% by SDS - PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Immunology
Molecular Weight :
26.9kDa (247aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
TLNSVLINSN AIKNLPPPLG GAGGQPGSAV SVAPGVLYEG GNKYQTLDNY QPYPCAEDEE CGSDEYCSSP SRGAAGVGGV QICLACRKRR KRCMRHAMCC PGNYCKNGIC MPSDHSHFPR GEIEESIIEN LGNDHNAAAG DGYPRRTTLT SKIYHTKGQE GSVCLRSSDC AAGLCCARHF WSKICKPVLK EGQVCTKHKR KGSHGLEIFQ RCYCGEGLAC RIQKDHHQAS NSSRLHTCQR
Tag :
His-Tag
Expression System :
HEK293
Predicted nterm :
Thr 32
Product Type Name :
Recombinant Protein
UniProt No. :
O54908
Internal Search Terms :
mDkk-1, Dkk-1, Dkk1, Dickkopf-related protein 1, Dickkopf-1, Dickkopf WNT signaling pathway inhibitor 1, ATGP4071-10ug, ATGP4071-20ug, ATGP4071-50ug, ATGP4071-100ug, ATGP4071-250ug, ATGP4071-500ug, ATGP4071-1mg, ATGP4071-010, ATGP4071-020, ATGP4071-050, ATGP4071-100, ATGP4071-250, ATGP4071-500, ATGP4071-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.