Recombinant human Akt3 protein | NKMAX ATGP4061 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Akt3 protein

catalog :

ATGP4061

quantity :

10 ug

price :

140 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Akt3 protein

Domain :

1-479aa

Catalog number (SKU) :

ATGP4061

NCBI :

NP_005456.1

Description :

Akt3, also known as RAC-gamma serine/threonine-protein kinase, is a member of the Akt subfamily of serine/threonine protein kinases. It is one of 3 closely related serine/threonine-protein kinases (Akt1, Akt2 and Akt3) called the Akt kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. Also this is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Akt3 is the least studied Akt isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. Recombinant human Akt3, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.

Alternative Names :

RAC-gamma serine/threonine-protein kinase, Protein kinase Akt-3, Protein kinase B gamma, PKB gamma, RAC-PK-gamma, STK-2, RAC-gamma serine/threonine-protein kinase isoform 1, v-akt murine thymoma viral oncogene homolog 3, MPPH, MPPH2, PKB-GAMMA, PKBG, PRKBG, RAC-gamma, AKT serine/threonine kinase 3

Concentration :

0.25mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Nakatani K., et al, (1999) J. Biol. Chem. 274: 21528–21532.;; Brodbeck D., et al, (1999) J.Biol. Chem. 274: 9133–9136.

Purity :

> 90% by SDS - PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

56.5kDa (485aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MSDVTIVKEG WVQKRGEYIK NWRPRYFLLK TDGSFIGYKE KPQDVDLPYP LNNFSVAKCQ LMKTERPKPN TFIIRCLQWT TVIERTFHVD TPEEREEWTE AIQAVADRLQ RQEEERMNCS PTSQIDNIGE EEMDASTTHH KRKTMNDFDY LKLLGKGTFG KVILVREKAS GKYYAMKILK KEVIIAKDEV AHTLTESRVL KNTRHPFLTS LKYSFQTKDR LCFVMEYVNG GELFFHLSRE RVFSEDRTRF YGAEIVSALD YLHSGKIVYR DLKLENLMLD KDGHIKITDF GLCKEGITDA ATMKTFCGTP EYLAPEVLED NDYGRAVDWW GLGVVMYEMM CGRLPFYNQD HEKLFELILM EDIKFPRTLS SDAKSLLSGL LIKDPNKRLG GGPDDAKEIM RHSFFSGVNW QDVYDKKLVP PFKPQVTSET DTRYFDEEFT AQTITITPPE KYDEDGMDCM DNERRPHFPQ FSYSASGRE

Tag :

His-Tag

Expression System :

HEK293

Predicted nterm :

Met 1

Product Type Name :

Recombinant Protein

UniProt No. :

Q9Y243

Internal Search Terms :

ATGP4061-10ug,ATGP4061-20ug,ATGP4061-50ug,ATGP4061-100ug,ATGP4061-250ug,ATGP4061-500ug,ATGP4061-1mg,ATGP4061-10,ATGP4061-20,ATGP4061-50,ATGP4061-100,ATGP4061-250,ATGP4061-500,ATGP4061-1

more info or order :

NKMAX product webpage