protein

Recombinant human Casein kinase 2 beta/CSNK2B protein

ATGP4047

10 ug

110 USD

Recombinant human Casein kinase 2 beta/CSNK2B protein

1-215aa

ATGP4047

NP_001311

Casein Kinase 2 (CK2, also called PKCK2) is a ubiquitous Ser/Thr kinase expressed in all eukaryotes. CK2 is a tetramer composed of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. It has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. The beta subunit itself does not have kinase activity, but confers stability to the CK2 alpha subunit and is involved in activity and substrate specificity. Recombinant human CK2beta was expressed in E. coli and purified by using conventional chromatography techniques.

Casein kinase 2 beta polypeptide, Casein kinase II subunit beta, CK II beta, Phosvitin, Protein G5a, Ckb1, Ckb2, CK2N, G5A

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.2M NaCl, 1mM DTT, 1mM EDTA

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Litchfield DW., et al. (2003). Biochem J. 369(1):1-15;; unger GM., et al. (2004). Curr. Cancer Drug Targets 4(1):77-84;;

> 95% by SDS-PAGE

SDS-PAGE

Human

Signal Transduction

24.9 kDa (215aa) confirmed by MALDI-TOF

MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR

Non-Tagged

E.coli

Recombinant Protein

P67870

Casein Kinase2 b, PKCK2 Beta, PKCK2B, CK2N, CSK2B, MGC138222, MGC138224, G5A, Phosvitin, Casein Kinase 2 beta, Casein Kinase 2B, Casein Kinase 2 beta, Casein kinase 2 beta polypeptide, Casein kinase II subunit beta, CK II beta, CK2B, CSNK 2B, CSNK2B, G5A,CKB0801-10ug,CKB0801-20ug,CKB0801-50ug,CKB0801-100ug,CKB0801-250ug,CKB0801-500ug,CKB0801-1mg,CKB0801-10,CKB0801-20,CKB0801-50,CKB0801-100,CKB0801-250,CKB0801-500,CKB0801-1,ATGP4047-10ug,ATGP4047-20ug,ATGP4047-50ug,ATGP4047-100ug,ATGP4047-250ug,ATGP4047-500ug,ATGP4047-1mg,ATGP4047-10,ATGP4047-20,ATGP4047-50,ATGP4047-100,ATGP4047-250,ATGP4047-500,ATGP4047-1

Matsumoto M, et al. CSNK2B modulates IRF1 binding to functional DNA elements and promotes basal and agonist-induced antiviral signaling. (Nucleic Acids Res. 2023){https://pubmed.ncbi.nlm.nih.gov/37094077/}