Recombinant human EphB1 protein | NKMAX ATGP4038 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human EphB1 protein

catalog :

ATGP4038

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human EphB1 protein

Domain :

18-540aa

Catalog number (SKU) :

ATGP4038

NCBI :

NP_004432.1

Description :

EphB1 also known as Ephrin type-B receptor 1, is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors. EphB1 has been shown to bind ephrin-B2, ephrin-B1,ephrin‑A3, ephrin-A1, ephrin-A4, and ephrin-B3. It binds to tyrosine kinase phosphorylates syndecan-2 and that this phosphorylation event is crucial for syndecan-2 clustering and spine formation. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. The ephrin/Eph families also appear to play a role in angiogenesis. Recombinant human EPHB1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Alternative Names :

EPHB-1, Ephrin type-B receptor 1, Eph Receptor B1, ELK, EPH tyrosine kinase 2, EPH-like kinase 6, EK6, hEK6, HEK6, Neuronally-expressed EPH-related tyrosine kinase, NET, NETHek6, Tyrosine-protein kinase receptor EPH-2, EPHT2, soluble EPHB1 variant 1

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Eph Nomenclature Committee. Cell 90:403-404.;; Pasquale, E.B. (1997) Curr. Opin. Cell Biol. 9:608-615.;;Adams RH, et al. (1999). Genes Dev. 13: 295-306.;;

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human EFNB1 (CAT# ATGP3800).

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Angiogenesis, Cardiovascular

Molecular Weight :

59.2 kDa (529aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human EPHB1 is coated at 2 ug/ml (100 ul/well) can bind Human EFNB1 (CAT# ATGP3800) in a Functional ELISA assay.

Amino Acid Sequence :

MEETLMDTRT ATAELGWTAN PASGWEEVSG YDENLNTIRT YQVCNVFEPN QNNWLLTTFI NRRGAHRIYT EMRFTVRDCS SLPNVPGSCK ETFNLYYYET DSVIATKKSA FWSEAPYLKV DTIAADESFS QVDFGGRLMK VNTEVRSFGP LTRNGFYLAF QDYGACMSLL SVRVFFKKCP SIVQNFAVFP ETMTGAESTS LVIARGTCIP NAEEVDVPIK LYCNGDGEWM VPIGRCTCKP GYEPENSVAC KACPAGTFKA SQEAEGCSHC PSNSRSPAEA SPICTCRTGY YRADFDPPEV ACTSVPSGPR NVISIVNETS IILEWHPPRE TGGRDDVTYN IICKKCRADR RSCSRCDDNV EFVPRQLGLT ECRVSISSLW AHTPYTFDIQ AINGVSSKSP FPPQHVSVNI TTNQAAPSTV PIMHQVSATM RSITLSWPQP EQPNGIILDY EIRYYEKEHN EFNSSMARSQ TNTARIDGLR PGMVYVVQVR ARTVAGYGKF SGKMCFQTLT DDDYKSELRE QLP

Tag :

His-Tag

Expression System :

HEK293

Predicted nterm :

Met18

Product Type Name :

Recombinant Protein

UniProt No. :

P54762

Internal Search Terms :

ATGP4038-10ug,ATGP4038-20ug,ATGP4038-50ug,ATGP4038-100ug,ATGP4038-250ug,ATGP4038-500ug,ATGP4038-1mg,ATGP4038-10,ATGP4038-20,ATGP4038-50,ATGP4038-100,ATGP4038-250,ATGP4038-500,ATGP4038-1

more info or order :

NKMAX product webpage