Recombinant porcine IFN-alpha 1/IFNA1 protein | NKMAX ATGP4031 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant porcine IFN-alpha 1/IFNA1 protein

catalog :

ATGP4031

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant porcine IFN-alpha 1/IFNA1 protein

Domain :

24-189aa

Catalog number (SKU) :

ATGP4031

NCBI :

NP_999558.1

Description :

IFN-alpha 1, also known as Interferon alpha-1, belongs to a family of cytokines with potent antiviral , antiproliferative and immunomodulatory properties. IFNs were originally discovered as molecules that could reduce the ability of a normal virus to infect cells, a process called viral interference. IFNs have been classified into two major types of IFNs, type I and type II, based on their interactions to a specific cell surface receptor. The type I IFNs bind to the interferon alpha receptor, which consists of two subunits, IFNAR1 and IFNAR2. The IFN-α proteins are produced mainly by plasmacytoid dendritic cells (pDCs). They are mainly involved in innate immunity against viral infection. It is also made synthetically as medication in hairy cell leukemia. Recombinant porcine IFN-alpha 1, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.

Alternative Names :

Interferon alpha-1, Interferon-alpha, IFN-alpha-1, IFNA1, IFN-ALPHA-1, IFN1@

Concentration :

1mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lengyel P (1982) Annual Review of Biochemistry. 51:252-282.;; Pestka S., et al, (1987) Annual Review of Biochemistry. 56:727–777.;; Isaacs A., et al, (1957) Biological Sciences. 147(927):258–267.

Purity :

> 90% by SDS - PAGE

Applications :

SDS-PAGE

Antigen Species :

Pocrine

Gene Category :

Immunology, Hormones & Cytokines

Molecular Weight :

20.2kDa (176aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

CDLPQT HSLAHTRALR LLAQMRRISP FSCLDHRRDF GSPHEAFGGN QVQKAQAMAL VHEMLQQTFQ LFSTEGSAAA WNESLLHQFC TGLDQQLRDL EACVMQEAGL EGTPLLEEDS ILAVRKYFHR LTLYLQEKSY SPCAWEIVRA EVMRSFSSSR NLQDRLRKKE

Tag :

His-Tag

Expression System :

HEK293

Predicted nterm :

Asp

Product Type Name :

Recombinant Protein

UniProt No. :

Q6VAB8

Internal Search Terms :

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more info or order :

NKMAX product webpage