Recombinant human Cathepsin F protein | NKMAX ATGP4026 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Cathepsin F protein

catalog :

ATGP4026

quantity :

10 ug

price :

99 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Cathepsin F protein

Domain :

20-484aa

Catalog number (SKU) :

ATGP4026

NCBI :

NP_003784

Description :

Cathepsin F, also known as CTSF, belongs to the cathepsin family. Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. This protein is thought to play a role in normal protein catabolism, and because it is highly expressed in some cancer cell lines, it may be involved in degradative processes occurring during tumor progression. The CTSF gene may function as a tumor suppressor in Gastric cancer and may be a potential therapeutic target in the treatment of Gastric cancer. It also can be used as an alternative way to test for the disease known as Opisthorchis Viverrini. Recombinant human Cathepsin F protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

CTSF, CATSF, CLN13

Concentration :

0.25mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 40% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Schmitz J., et al, (2015) ChemMedChem. 10:1365-1377.;; Ji C., et al, (2018) Oncol Res. 26:83-93.;; Kulkarni G., et al, (2021) Schizophr Res. 228:435-437.;;

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 5 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1pmole of Z-Phe-Arg-AMC to Z-Phe-Arg and AMC per minute at pH 5.0 at 37℃.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

52.5kDa (474aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Specific activity is > 5 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1pmole of Z-Phe-Arg-AMC to Z-Phe-Arg and AMC per minute at pH 5.0 at 37℃.

Amino Acid Sequence :

APAQPRA ASFQAWGPPS PELLAPTRFA LEMFNRGRAA GTRAVLGLVR GRVRRAGQGS LYSLEATLEE PPCNDPMVCR LPVSKKTLLC SFQVLDELGR HVLLRKDCGP VDTKVPGAGE PKSAFTQGSA MISSLSQNHP DNRNETFSSV ISLLNEDPLS QDLPVKMASI FKNFVITYNR TYESKEEARW RLSVFVNNMV RAQKIQALDR GTAQYGVTKF SDLTEEEFRT IYLNTLLRKE PGNKMKQAKS VGDLAPPEWD WRSKGAVTKV KDQGMCGSCW AFSVTGNVEG QWFLNQGTLL SLSEQELLDC DKMDKACMGG LPSNAYSAIK NLGGLETEDD YSYQGHMQSC NFSAEKAKVY INDSVELSQN EQKLAAWLAK RGPISVAINA FGMQFYRHGI SRPLRPLCSP WLIDHAVLLV GYGNRSDVPF WAIKNSWGTD WGEKGYYYLH RGSGACGVNT MASSAVVD

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q9UBX1

Internal Search Terms :

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more info or order :

NKMAX product webpage