product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse OX40 Ligand/TNFSF4 Protein
catalog :
ATGP4022
quantity :
10 ug
price :
150 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant mouse OX40 Ligand/TNFSF4 Protein
Domain :
51-198aa
Catalog number (SKU) :
ATGP4022
NCBI :
NP_033478
Description :
OX40 Ligand, also known as Inositol monophosphatase 3, is a member of the tumor necrosis factor (TNF) receptor family. It is expressed on many antigen-presenting cells such as DC2s, macrophages, and activated B lymphocytes. The receptor for OX40L is OX40 that is expressed predominantly on activated CD4+ T cells. Expression of OX40 is transient following engagement of T cell receptors. The ligation of OX40-OX40L is a source of survival signal for T cells and enables the development of memory T cells. Also, It stimulates proliferation and differentiation of activated B cells, and increases immunoglobulin secretion. OX40-OX40 Ligand signaling is involved in graft-versus-host disease and autoimmune disease . Mutations in OX40 and OX40 Ligand are associated with cardiovascular disease. Recombinant mouse OX40 Ligand, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Tumor necrosis factor superfamily member 4, Ath1, Ath-1, CD134L, OX40 ligand, OX40L, 34kD tax-transcriptionally activated glycoprotein 1, gp34, TXGP1, Txgp1l, CD252
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Damayanti T., et al, (2010) Am. J. Respir. Crit. Care Med. 181(7):688-698. ;; Ishii N., et al, (2010) Adv. Immunol. 105:63-98.
Purity :
> 90% by SDS - PAGE
Bioactivity Comment Only :
Measured by its binding ability in a functional ELISA with Human TNFRSF4 (CAT# ATGP4045).
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Mouse
Gene Category :
Immunology
Molecular Weight :
17.7kDa (157aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Mouse TNFSF4 is coated at 1 ug/ml (100 ul/well) can bind Human TNFRSF4 (CAT# ATGP4045) in a Functional ELISA assay.
Amino Acid Sequence :
SSSPAKD PPIQRLRGAV TRCEDGQLFI SSYKNEYQTM EVQNNSVVIK CDGLYIIYLK GSFFQEVKID LHFREDHNPI SIPMLNDGRR IVFTVVASLA FKDKVYLTVN APDTLCEHLQ INDGELIVVQ LTPGYCAPEG SYHSTVNQVP L
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
P43488
Internal Search Terms :
ATGP4022-10ug,ATGP4022-20ug,ATGP4022-50ug,ATGP4022-100ug,ATGP4022-250ug,ATGP4022-500ug,ATGP4022-1mg, ATGP4022-10,ATGP4022-20,ATGP4022-50,ATGP4022-100,ATGP4022-250,ATGP4022-500,ATGP4022-1,ATGP4022-10ug,ATGP4022-20ug,ATGP4022-50ug,ATGP4022-100ug,ATGP4022-250ug,ATGP4022-500ug,ATGP4022-1mg,ATGP4022-10,ATGP4022-20,ATGP4022-50,ATGP4022-100,ATGP4022-250,ATGP4022-500,ATGP4022-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.