Recombinant human CD47 protein | NKMAX ATGP4015 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD47 protein

catalog :

ATGP4015

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD47 protein

Domain :

19-141aa

Catalog number (SKU) :

ATGP4015

NCBI :

NP_001768

Description :

CD47, also known as leukocyte surface antigen CD47 isoform 1, has a role in both cell adhesions by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Recombinant human CD47, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

CD47, OA3, IAP, MER6, Leukocyte surface antigen CD47 isoform 1, antigenic surface determinant protein OA3, Integrin-associated protein

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Iwamoto C et al., (2014) Exp. Hematol. 42(3):163-171.;; Wang Y et al., (2013) Mol. Ther. 21(10):1919-1929.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human SIRP gamma/CD172g (CAT# ATGP4030)

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology, Adhesion & Movement

Molecular Weight :

14.7 kDa (129aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human CD47 is coated at 1 ug/ml (100 ul/well) can bind Human SIRP gamma/CD172g (CAT# ATGP4030) in a Functional ELISA assay.

Amino Acid Sequence :

QLLFNKTKSV EFTFCNDTVV IPCFVTNMEA QNTTEVYVKW KFKGRDIYTF DGALNKSTVP TDFSSAKIEV SQLLKGDASL KMDKSDAVSH TGNYTCEVTE LTREGETIIE LKYRVVSWFS PNE

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Gln19

Product Type Name :

Recombinant Protein

UniProt No. :

Q08722

Internal Search Terms :

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more info or order :

NKMAX product webpage