Recombinant mouse ACE-2 protein | NKMAX ATGP4014 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse ACE-2 protein

catalog :

ATGP4014

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse ACE-2 protein

Domain :

18-740aa

Catalog number (SKU) :

ATGP4014

NCBI :

NP_081562.2

Description :

ACE-2, also known as angiotensin-converting enzyme 2, is an integral membrane protein and a zinc metalloprotease of the ACE family that also includes somatic and germinal ACE. It cleaves angiotensin 1 to angiotensin 1-9 and angiotensin 2 to angiotensin 1-7 as a carboxypeptidase. It may be an important regulator of heart function and have a protective role in acute lung injury. Also, it is a key SARS-CoV Spike protein receptor in vivo. Recombinant mouse ACE-2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, Processed Angiotensin-converting enzyme 2, ACE2, 2010305L05Rik

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kuba K., et al. (2005) Nature Med. 11:875-879.;; Ima Y., et al. (2005) Nature 436:112-116.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 200 pmol/min/ug, and is defined as the amount of enzyme that hydrolysis 1.0 pmole of Mca-YVADAPK(Dnp)-OH per minute at pH 7.5, at 25C.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Mouse

Gene Category :

Enzymes & Proteases

Molecular Weight :

84.5 kDa (731aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QSLTEENAKT FLNNFNQEAE DLSYQSSLAS WNYNTNITEE NAQKMSEAAA KWSAFYEEQS KTAQSFSLQE IQTPIIKRQL QALQQSGSSA LSADKNKQLN TILNTMSTIY STGKVCNPKN PQECLLLEPG LDEIMATSTD YNSRLWAWEG WRAEVGKQLR PLYEEYVVLK NEMARANNYN DYGDYWRGDY EAEGADGYNY NRNQLIEDVE RTFAEIKPLY EHLHAYVRRK LMDTYPSYIS PTGCLPAHLL GDMWGRFWTN LYPLTVPFAQ KPNIDVTDAM MNQGWDAERI FQEAEKFFVS VGLPHMTQGF WANSMLTEPA DGRKVVCHPT AWDLGHGDFR IKMCTKVTMD NFLTAHHEMG HIQYDMAYAR QPFLLRNGAN EGFHEAVGEI MSLSAATPKH LKSIGLLPSD FQEDSETEIN FLLKQALTIV GTLPFTYMLE KWRWMVFRGE IPKEQWMKKW WEMKREIVGV VEPLPHDETY CDPASLFHVS NDYSFIRYYT RTIYQFQFQE ALCQAAKYNG SLHKCDISNS TEAGQKLLKM LSLGNSEPWT KALENVVGAR NMDVKPLLNY FQPLFDWLKE QNRNSFVGWN TEWSPYADQS IKVRISLKSA LGANAYEWTN NEMFLFRSSV AYAMRKYFSI IKNQTVPFLE EDVRVSDLKP RVSFYFFVTS PQNVSDVIPR SEVEDAIRMS RGRINDVFGL NDNSLEFLGI HPTLEPPYQPPVT

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Gln18

Product Type Name :

Recombinant Protein

UniProt No. :

Q8R0I0

Internal Search Terms :

ATGP3288,ATGP4014-10ug,ATGP4014-20ug,ATGP4014-50ug,ATGP4014-100ug,ATGP4014-250ug,ATGP4014-500ug,ATGP4014-1mg, ATGP4014-10,ATGP4014-20,ATGP4014-50,ATGP4014-100,ATGP4014-250,ATGP4014-500,ATGP4014-1,ATGP4014-10ug,ATGP4014-20ug,ATGP4014-50ug,ATGP4014-100ug,ATGP4014-250ug,ATGP4014-500ug,ATGP4014-1mg,ATGP4014-10,ATGP4014-20,ATGP4014-50,ATGP4014-100,ATGP4014-250,ATGP4014-500,ATGP4014-1

more info or order :

NKMAX product webpage