Recombinant human CD6 protein | NKMAX ATGP4005 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD6 protein

catalog :

ATGP4005

quantity :

10 ug

price :

77 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD6 protein

Domain :

18-402aa

Catalog number (SKU) :

ATGP4005

NCBI :

NP_006716

Description :

CD6, also known as T-cell differentiation antigen CD6, is a member of the group B SRCR (scavenger receptor cysteine-rich) superfamily. CD6 is a cell surface glycoprotein expressed primarily on T cells and It expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. And T-cell differentiation antigen CD6 appears to play a role as both a co-stimulatory molecule in T cell activation and as an adhesion receptor. CD6 binds to CD166(known as ALCAM), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. Certain alleles of this protein may be associated with susceptibility to multiple sclerosis. Recombinant human CD6, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

T-cell differentiation antigen CD6, T12, TP120, CD6, CD_antigen, T-cell differentiation antigen CD6 isform1

Concentration :

0.5mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Singer, N.G. et al. (1996) Immunology 88:537-547.;; Namir J Hassan et al. (2004) Eur J Immunol. 34:930-940.;;

Purity :

90% by SDS - PAGE

Bioactivity Comment Only :

Measured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells. When cells are added to human CD6 coated plates 10 ug/ml. This effect is more to 50%.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

68.3kDa (627aa)

Endotoxin :

<1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

HPSPAPP DQLNTSSAES ELWEPGERLP VRLTNGSSSC SGTVEVRLEA SWEPACGALW DSRAAEAVCR ALGCGGAEAA SQLAPPTPEL PPPPAAGNTS VAANATLAGA PALLCSGAEW RLCEVVEHAC RSDGRRARVT CAENRALRLV DGGGACAGRV EMLEHGEWGS VCDDTWDLED AHVVCRQLGC GWAVQALPGL HFTPGRGPIH RDQVNCSGAE AYLWDCPGLP GQHYCGHKED AGAVCSEHQS WRLTGGADRC EGQVEVHFRG VWNTVCDSEW YPSEAKVLCQ SLGCGTAVER PKGLPHSLSG RMYYSCNGEE LTLSNCSWRF NNSNLCSQSL AARVLCSASR SLHNLSTPEV PASVQTVTIE SSVTVKIENK ESRELMLL

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P30203

Internal Search Terms :

ATGP4005-10ug, ATGP4005-50ug, ATGP4005-100ug, ATGP4005-200ug, ATGP4005-250ug, ATGP4005-500ug, ATGP4005-1mg,ATGP4005-10ug,ATGP4005-20ug,ATGP4005-50ug,ATGP4005-100ug,ATGP4005-250ug,ATGP4005-500ug,ATGP4005-1mg,ATGP4005-10,ATGP4005-20,ATGP4005-50,ATGP4005-100,ATGP4005-250,ATGP4005-500,ATGP4005-1

more info or order :

NKMAX product webpage