Recombinant human CD299/CLEC4M protein | NKMAX ATGP3998 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD299/CLEC4M protein

catalog :

ATGP3998

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD299/CLEC4M protein

Domain :

72-399aa

Catalog number (SKU) :

ATGP3998

NCBI :

NP_055072

Description :

CD299, as known as DC-SIGNR and CLEC4M, is a type II integral membrane protein that is 77% amino acid identical to CD209/DC-SIGN, an HIV gp120-binding protein. This protein is probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. It may mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. CD299 is a receptor for ICAM3, binding to mannose-like carbohydrates. It also recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. Recombinant human CD299, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

C-type lectin domain family 4 member M, CD209 antigen-like protein 1, DC-SIGN-related protein, DC-SIGNR, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, DC-SIGN2, Liver/lymph node-specific ICAM-3-grabbing non-integrin, L-SIGN, CD209L, CD209L1

Concentration :

0.5mg/ml (determined by Absorbance at 280nm)

Formulation :

Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Gijzen K., et al, (2008) Exp Hematol. 36:860-870.;; Johnson TR, et al, (2012) J Virol. 86:1339-1347.;; Xia HB, et al, (2020) Oncol Lett. 19:69-76.;;

Purity :

> 95% by SDS - PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

64.8kDa (570aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

VSKVPSS LSQEQSEQDA IYQNLTQLKA AVGELSEKSK LQEIYQELTQ LKAAVGELPE KSKLQEIYQE LTRLKAAVGE LPEKSKLQEI YQELTRLKAA VGELPEKSKL QEIYQELTRL KAAVGELPEK SKLQEIYQEL TELKAAVGEL PEKSKLQEIY QELTQLKAAV GELPDQSKQQ QIYQELTDLK TAFERLCRHC PKDWTFFQGN CYFMSNSQRN WHDSVTACQE VRAQLVVIKT AEEQNFLQLQ TSRSNRFSWM GLSDLNQEGT WQWVDGSPLS PSFQRYWNSG EPNNSGNEDC AEFSGSGWND NRCDVDNYWI CKKPAACFRD E

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q9H2X3

Internal Search Terms :

CLEC4M,ATGP3998-10ug,ATGP3998-20ug,ATGP3998-50ug,ATGP3998-100ug,ATGP3998-250ug,ATGP3998-500ug,ATGP3998-1mg,ATGP3998-10,ATGP3998-20,ATGP3998-50,ATGP3998-100,ATGP3998-250,ATGP3998-500,ATGP3998-1

more info or order :

NKMAX product webpage